Stereochemistry of Organic Compounds: Principles and Applications - Hardcover

Nasipuri, D.

Hardcover

ISBN 10: 190657491X ISBN 13: 9781906574918

Publisher: New Academic Science, 2012

Synopsis

KEY FEATURES:

* Subject treated from fundamental and developed to the latest developments.
* A large cross-section of organic reactions/mechanisms given with stereochemical implications.
* Relationship between conformation and reactivity specially highlighted.
* Instrumentation techniques relating to stereochemical investigation discussed in simple language.

ABOUT THE BOOK:

During recent years, stereochemistry has undergone a phenomenal growth both in theory and practice, with a concomitant increase of interest among the organic chemists, biological chemists, medicinal chemists, and pharmacologists. The present text provides an up-to-date, coherent, and comprehensive account of the subject starting from the fundamentals and leading up to the latest developments as far as practicable. Emphasis has been placed on a symmetry-based approach to molecular chirality, stereochemical terminologies (modern stereochemistry is replete with them), topicity and prostereoisomerism, conformational analysis, dynamic stereochemistry, chiroptical properties, and assignment of absolute configuration to chiral molecules. Dynamic stereochemistry has been discussed with reference to conformation-reactivity correlation, stereoselective synthesis, and pericyclic reactions. A large cross-section of organic reactions with stereochemical implication has been incorporated. Attempts have been made to familiarise the readers with modern instrumental techniques, nuclear magnetic resonance in particular, used for stereochemical investigation. Each chapter is provided with a summary which highlights the main points of the text.

CONTENTS:

* Molecular Geometry and Chemical Bonding
* Molecular Symmetry and Chirality
* Stereoisomerism: Definitions and Classifications
* Stereoisomerism and Centre of Chirality
* Stereoisomerism: Axial Chirality, Planar Chirality and Helicity
* Topicity and Prostereoisomerism
* Racemisation and Methods of Resolution
* Determination of Configuration
* Conformations of Acyclic Molecules
* Conformations of Cyclic Systems: Monocyclic Compounds
* Conformations of Cyclic Systems: Fused Ring and Bridged Ring Compounds
* Dynamic Stereochemistry I: Conformation and Reactivity
* Dynamic Stereochemistry II:Stereoselective Reactions
* Dynamic Stereochemistry III:Pericyclic Reactions
* Molecular Dissymmetry and Chiroptical Properties
* Molecular Recognition: Chemical and Stereochemical Aspects

READERSHIP:

* Graduate and postgraduate students of Chemistry courses
* University and college libraries
* Biochemists, Medical and Pharmacology students and other related professionals

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About this title

About the Author

Dr D Nasipuri is a retired Professor and Chairman in the Department of Chemistry, Indian Institute of Technology, Kharagpur. He received his PhD (1955) and DSc (1964) degrees from the University of Calcutta where he was a Faculty member since 1950. He moved to IIT, Kharagpur in 1969 as a Professor of Chemistry and retired in 1985. Since 1986, he worked in the Indian Institute of Chemical Biology first as a Senior Scientist, Indian National Science Academy and then as an Emeritus Scientist, CSIR. He collaborated with two very distinguished scientists, Professor A.J. Birch in the University Manchester, UK and Professor E.L Eliel in the University of Notre Dame, USA. In different times, he had been a Leverhulme visiting fellow in the University of New South Wales, Australia, a Senior Royal Society Bursar Fellow in Oxford University, a guest scientist in Warsaw under the Polish Academy of Sciences, twice a visiting scientist in the University of North Carolina, Chapel Hill, USA, and a visiting professor in the University of Toronto, Canada. His main research interests are in the areas of organic synthesis and stereochemistry, especially in asymmetric synthesis in which he is a pioneer. He was a fellow of the Royal Society of Chemistry, London, and Member of the New York Academy of Sciences, USA.

Edition details

• Publisher: New Academic Science
• Publication date: 2012
• Language: English
• ISBN 10: 190657491X
• ISBN 13: 9781906574918
• Binding: Hardcover
• Edition number: 4
• Number of pages: 537