Mass Spectral and GC Data of Drugs, Poisons, Pesticides, Pollutants and Their Metabolites - Hardcover

Maurer, Hans H.; Pfleger, Karl; Weber, Armin A.

9783527315383: Mass Spectral and GC Data of Drugs, Poisons, Pesticides, Pollutants and Their Metabolites

Hardcover

ISBN 10: 3527315381 ISBN 13: 9783527315383

Publisher: Wiley-VCH, 2007

This unique collection contains data obtained from clinical samples over the course of more than 20 years. It encompasses 7500 potentially harmful substances, from simple analgesics to designer drugs, and from pesticides to chemical warfare agents. Since these substances are often broken down in the human body, metabolites are also included, so as to allow quick and unambiguous identification of the mother substance.

The 3rd edition gives all spectra in order of their molecular mass, since this has become the prime benchmark criterion for the identification of unknown substances.

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From the Back Cover:

The gold standard in clinical mass spectrometry is now completely redesigned for easier access and condensed to accommodate the world`s most comprehensive reference in a handy two volumes.

More than 1500 new spectra of novel designer drugs, pharmaceuticals and their metabolites have been added, bringing the total up to 7,840 clinically important substances.
With more than 3300 metabolite substances measured, this is the most comprehensive collection of metabolite data ever published.
All substances are classifi ed according to their toxicological categories, greatly helping the clinical researcher to identify and evaluate unknown samples.

Volume 1 contains an overview on experimental methods, plus compound listings by name and substance category. The second volume contains the data for each substance, listed in order of mass, including structural formula, empirical formula and exact mass, GC retention index and detection methods, compound category and sample type, and CAS registry number. A truly unique collection of data obtained over the course of more than two decades.

Praise for the previous edition:

"An invaluable source of reference for any environmental, toxicological or analytical laboratory."
—Rapid Communications in MS

"The excellent organization of the information facilitates their everyday use. Highly recommended."
—Environmental Science and Pollution Research

"The modern toxicological laboratory can ill afford to be without this unique work."
—Veterinary Human Toxicology

About the Author:

Karl Pfleger was appointed head of the Department of Toxicology at the Saarland University in Homburg/Saar, Germany, in 1967. In the late 1970s he developed, together with his PhD student Hans H. Maurer, novel analysis procedures for identification and Quantification of drugs, poisons and their metabolites in body samples. they introduced mass spectrometry as the gold standard into clinical and forensic toxicology. In 1985, they published the first edition of their unique handbook of GC and MS data together with Armin A. Weber (left), who was and is responsible for all technical and software developments, including the mass spectral database that was developed from the printed collection. In 1987, Karl Pfleger received the Jean-Servais Stas Medal of the Gesellschaft fur Toxikologische und Forensische Chemie (GTFCh). In 1992, Karl Pfleger retired and Hans H. Maurer became his successor as professor and head of the department. His main areas of research are analytical toxicology (GC-MS, LC-MS) and metabolism of xenobiotics. He has published over 130 original papers and 20 invited reviews. He has received several scientific awards, including the Young Investigator Award of the Homburg Medical Faculty in 1983, the Irving Sunshine Award for Outstanding Contributions to Clinical Toxicology of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT) in 1997, the Alan Curry Lifetime Achievement Award of The International Association of Forensic Toxicologists (TIAFT) for Outstanding Contributions to Forensic Toxicology in 2003, and the Doctor Honoris causa title of the University of Ghent in 2007. He is the current President of IATDMCT (since 2007), Councillor of TIAFT (since 2005) and treasurer of GTFCh (since 1987).

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