Jembrana Disease Virus Transactivator

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9783639035049: Jembrana Disease Virus Transactivator

Jembrana disease virus (JDV) is a lentivirus with the smallest genome identified thus far. Unlike its closely relative Bovine Immunodeficiency Virus (BIV), JDV causes an acute and lethal infection specific to Bali cattle in Indonesia; a high plasma viral load coincides with the acute disease syndrome. The text describes studies on the JDV Tat, a small protein crucial for replication which upregulates the transcription of viral genome from its cognate promoter. The multiple splicing events of tat transcription leading to the production of a tat protein were investigated in vivo during the early acute phase of the disease. Sequence conservation of regions which are predicted to have important roles in RNA binding and transcription activation were demonstrated using 3 geographical JDV strains. Aspects of the antibody response were examined in naturally or experimentally infected cattle. The role of the JDV Tat in the pathogenesis of Jembrana disease and its potential use in disease control were discussed. The text represents valuable contribution to the field of lentivirology and should be of interest to students and scientists involved in basic or applied virology researches.

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Lecturer and researcher in Virology at the Department of Infectious Diseases and Veterinary Public Health, Faculty of Veterinary Medicine, Bogor Agricultural University, Indonesia

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Setiyaningsih, Surachmi
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Setiyaningsih, Surachmi
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Book Description Book Condition: New. Publisher/Verlag: VDM Verlag Dr. Müller | Molecular and Immunogenicity Analysis | Jembrana disease virus (JDV) is a lentivirus with the smallest genome identified thus far. Unlike its closely relative Bovine Immunodeficiency Virus (BIV), JDV causes an acute and lethal infection specific to Bali cattle in Indonesia; a high plasma viral load coincides with the acute disease syndrome. The text describes studies on the JDV Tat, a small protein crucial for replication which upregulates the transcription of viral genome from its cognate promoter. The multiple splicing events of tat transcription leading to the production of a tat protein were investigated in vivo during the early acute phase of the disease. Sequence conservation of regions which are predicted to have important roles in RNA binding and transcription activation were demonstrated using 3 geographical JDV strains. Aspects of the antibody response were examined in naturally or experimentally infected cattle. The role of the JDV Tat in the pathogenesis of Jembrana disease and its potential use in disease control were discussed. The text represents valuable contribution to the field of lentivirology and should be of interest to students and scientists involved in basic or applied virology researches. | Format: Paperback | Language/Sprache: english | 185 gr | 132 pp. Bookseller Inventory # K9783639035049

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Surachmi Setiyaningsih
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Book Description VDM Verlag, 2008. PAP. Book Condition: New. New Book. Shipped from US within 10 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Bookseller Inventory # IQ-9783639035049

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Book Description VDM Verlag, 2008. PAP. Book Condition: New. New Book. Delivered from our UK warehouse in 3 to 5 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Bookseller Inventory # LQ-9783639035049

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Surachmi Setiyaningsih
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Book Description VDM Verlag Dr. Mueller e.K., Germany, 2008. Paperback. Book Condition: New. Language: English . Brand New Book ***** Print on Demand *****.Jembrana disease virus (JDV) is a lentivirus with the smallest genome identified thus far. Unlike its closely relative Bovine Immunodeficiency Virus (BIV), JDV causes an acute and lethal infection specific to Bali cattle in Indonesia; a high plasma viral load coincides with the acute disease syndrome. The text describes studies on the JDV Tat, a small protein crucial for replication which upregulates the transcription of viral genome from its cognate promoter. The multiple splicing events of tat transcription leading to the production of a tat protein were investigated in vivo during the early acute phase of the disease. Sequence conservation of regions which are predicted to have important roles in RNA binding and transcription activation were demonstrated using 3 geographical JDV strains. Aspects of the antibody response were examined in naturally or experimentally infected cattle. The role of the JDV Tat in the pathogenesis of Jembrana disease and its potential use in disease control were discussed. The text represents valuable contribution to the field of lentivirology and should be of interest to students and scientists involved in basic or applied virology researches. Bookseller Inventory # AAV9783639035049

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Surachmi Setiyaningsih
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Book Description VDM Verlag Aug 2008, 2008. Taschenbuch. Book Condition: Neu. Neuware - Jembrana disease virus (JDV) is a lentivirus with the smallest genome identified thus far. Unlike its closely relative Bovine Immunodeficiency Virus (BIV), JDV causes an acute and lethal infection specific to Bali cattle in Indonesia; a high plasma viral load coincides with the acute disease syndrome. The text describes studies on the JDV Tat, a small protein crucial for replication which upregulates the transcription of viral genome from its cognate promoter. The multiple splicing events of tat transcription leading to the production of a tat protein were investigated in vivo during the early acute phase of the disease. Sequence conservation of regions which are predicted to have important roles in RNA binding and transcription activation were demonstrated using 3 geographical JDV strains. Aspects of the antibody response were examined in naturally or experimentally infected cattle. The role of the JDV Tat in the pathogenesis of Jembrana disease and its potential use in disease control were discussed. The text represents valuable contribution to the field of lentivirology and should be of interest to students and scientists involved in basic or applied virology researches. 132 pp. Englisch. Bookseller Inventory # 9783639035049

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Surachmi Setiyaningsih
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Book Description VDM Verlag Aug 2008, 2008. Taschenbuch. Book Condition: Neu. Neuware - Jembrana disease virus (JDV) is a lentivirus with the smallest genome identified thus far. Unlike its closely relative Bovine Immunodeficiency Virus (BIV), JDV causes an acute and lethal infection specific to Bali cattle in Indonesia; a high plasma viral load coincides with the acute disease syndrome. The text describes studies on the JDV Tat, a small protein crucial for replication which upregulates the transcription of viral genome from its cognate promoter. The multiple splicing events of tat transcription leading to the production of a tat protein were investigated in vivo during the early acute phase of the disease. Sequence conservation of regions which are predicted to have important roles in RNA binding and transcription activation were demonstrated using 3 geographical JDV strains. Aspects of the antibody response were examined in naturally or experimentally infected cattle. The role of the JDV Tat in the pathogenesis of Jembrana disease and its potential use in disease control were discussed. The text represents valuable contribution to the field of lentivirology and should be of interest to students and scientists involved in basic or applied virology researches. 132 pp. Englisch. Bookseller Inventory # 9783639035049

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Surachmi Setiyaningsih
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Book Description VDM Verlag. Paperback. Book Condition: New. 132 pages. Dimensions: 8.7in. x 5.9in. x 0.3in.Jembrana disease virus (JDV) is a lentivirus with the smallest genome identified thus far. Unlike its closely relative Bovine Immunodeficiency Virus (BIV), JDV causes an acute and lethal infection specific to Bali cattle in Indonesia; a high plasma viral load coincides with the acute disease syndrome. The text describes studies on the JDV Tat, a small protein crucial for replication which upregulates the transcription of viral genome from its cognate promoter. The multiple splicing events of tat transcription leading to the production of a tat protein were investigated in vivo during the early acute phase of the disease. Sequence conservation of regions which are predicted to have important roles in RNA binding and transcription activation were demonstrated using 3 geographical JDV strains. Aspects of the antibody response were examined in naturally or experimentally infected cattle. The role of the JDV Tat in the pathogenesis of Jembrana disease and its potential use in disease control were discussed. The text represents valuable contribution to the field of lentivirology and should be of interest to students and scientists involved in basic or applied virology researches. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Paperback. Bookseller Inventory # 9783639035049

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