The Dynamic of Glucose-Insulin Endocrine Metabolic Regulatory System: A System Dynamics Approach

 
9783639103250: The Dynamic of Glucose-Insulin Endocrine Metabolic Regulatory System: A System Dynamics Approach

Diabetes mellitus is a disease in the glucose-insulin endocrine metabolic regulatory system, in which the pancreas either does not release insulin or does not properly use insulin to uptake glucose in the plasma, which is referred as hyperglycemia. Complications of diabetes mellitus include retinopathy, nephropathy, peripheral neuropathy and blindness. The purpose of this study is to model the dynamic of the short-term glucose regulatory system (GRS) in man and its hormonal regulation by considering all the feedback loops which are responsible of controlling the glucose metabolism in man. The model proposed in this work used the system dynamics (SD) approach which was designed for studying complex systems. This SD model consists of twenty-three negative (balance) loops and six compartments. The model was validated during wide range of clinical test inputs, to be sure that this model accurately represents the really endocrine system. Understanding the mechanism underlying glucose-insulin oscillations and determination of the origin of the glucose¿insulin levels oscillations is another purpose of this model. Other applications for this model also have been explored.

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ENG. Fadhl Mohamed Al-akwa is a Biomedical Engineer, Cairo University, Egypt (2003) . Eng. Al-Akwaa joined University of Science &Technology in 2006 where he is currently assistance lecturer. His research interests are Glucose Regulatory System, Gene Regulatory Network, Graphical Modeling, and Bioinformatics.

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Book Description Book Condition: New. Publisher/Verlag: VDM Verlag Dr. Müller | A System Dynamics Approach | Diabetes mellitus is a disease in the glucose-insulinendocrine metabolic regulatory system, in which thepancreas either does not release insulin or does notproperly use insulin to uptake glucose in the plasma,which is referred as hyperglycemia. Complications ofdiabetes mellitus include retinopathy, nephropathy,peripheral neuropathy and blindness. The purpose ofthis study is to model the dynamic of the short-termglucose regulatory system (GRS) in man and itshormonal regulation by considering all the feedbackloops which are responsible of controlling theglucose metabolism in man. The model proposed in thiswork used the system dynamics (SD) approach which wasdesigned for studying complex systems. This SD modelconsists of twenty-three negative (balance) loops andsix compartments. The model was validated during widerange of clinical test inputs, to be sure that thismodel accurately represents the really endocrinesystem. Understanding the mechanism underlyingglucose-insulin oscillations and determination of theorigin of the glucose insulin levels oscillations isanother purpose of this model.Other applications for this model also have beenexplored. | Format: Paperback | Language/Sprache: english | 156 pp. Bookseller Inventory # K9783639103250

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Book Description VDM Verlag, Germany, 2008. Paperback. Book Condition: New. Language: English . Brand New Book ***** Print on Demand *****.Diabetes mellitus is a disease in the glucose-insulin endocrine metabolic regulatory system, in which the pancreas either does not release insulin or does not properly use insulin to uptake glucose in the plasma, which is referred as hyperglycemia. Complications of diabetes mellitus include retinopathy, nephropathy, peripheral neuropathy and blindness. The purpose of this study is to model the dynamic of the short-term glucose regulatory system (GRS) in man and its hormonal regulation by considering all the feedback loops which are responsible of controlling the glucose metabolism in man. The model proposed in this work used the system dynamics (SD) approach which was designed for studying complex systems. This SD model consists of twenty-three negative (balance) loops and six compartments. The model was validated during wide range of clinical test inputs, to be sure that this model accurately represents the really endocrine system. Understanding the mechanism underlying glucose-insulin oscillations and determination of the origin of the glucose-insulin levels oscillations is another purpose of this model. Other applications for this model also have been explored. Bookseller Inventory # AAV9783639103250

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Book Description VDM Verlag Nov 2008, 2008. Taschenbuch. Book Condition: Neu. Neuware - Diabetes mellitus is a disease in the glucose-insulin endocrine metabolic regulatory system, in which the pancreas either does not release insulin or does not properly use insulin to uptake glucose in the plasma, which is referred as hyperglycemia. Complications of diabetes mellitus include retinopathy, nephropathy, peripheral neuropathy and blindness. The purpose of this study is to model the dynamic of the short-term glucose regulatory system (GRS) in man and its hormonal regulation by considering all the feedback loops which are responsible of controlling the glucose metabolism in man. The model proposed in this work used the system dynamics (SD) approach which was designed for studying complex systems. This SD model consists of twenty-three negative (balance) loops and six compartments. The model was validated during wide range of clinical test inputs, to be sure that this model accurately represents the really endocrine system. Understanding the mechanism underlying glucose-insulin oscillations and determination of the origin of the glucose insulin levels oscillations is another purpose of this model. Other applications for this model also have been explored. 156 pp. Deutsch. Bookseller Inventory # 9783639103250

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Book Description VDM Verlag Nov 2008, 2008. Taschenbuch. Book Condition: Neu. Neuware - Diabetes mellitus is a disease in the glucose-insulin endocrine metabolic regulatory system, in which the pancreas either does not release insulin or does not properly use insulin to uptake glucose in the plasma, which is referred as hyperglycemia. Complications of diabetes mellitus include retinopathy, nephropathy, peripheral neuropathy and blindness. The purpose of this study is to model the dynamic of the short-term glucose regulatory system (GRS) in man and its hormonal regulation by considering all the feedback loops which are responsible of controlling the glucose metabolism in man. The model proposed in this work used the system dynamics (SD) approach which was designed for studying complex systems. This SD model consists of twenty-three negative (balance) loops and six compartments. The model was validated during wide range of clinical test inputs, to be sure that this model accurately represents the really endocrine system. Understanding the mechanism underlying glucose-insulin oscillations and determination of the origin of the glucose insulin levels oscillations is another purpose of this model. Other applications for this model also have been explored. 156 pp. Deutsch. Bookseller Inventory # 9783639103250

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Book Description VDM Verlag. Paperback. Book Condition: New. 156 pages. Dimensions: 8.7in. x 5.9in. x 0.4in.Diabetes mellitus is a disease in the glucose-insulin endocrine metabolic regulatory system, in which the pancreas either does not release insulin or does not properly use insulin to uptake glucose in the plasma, which is referred as hyperglycemia. Complications of diabetes mellitus include retinopathy, nephropathy, peripheral neuropathy and blindness. The purpose of this study is to model the dynamic of the short-term glucose regulatory system (GRS) in man and its hormonal regulation by considering all the feedback loops which are responsible of controlling the glucose metabolism in man. The model proposed in this work used the system dynamics (SD) approach which was designed for studying complex systems. This SD model consists of twenty-three negative (balance) loops and six compartments. The model was validated during wide range of clinical test inputs, to be sure that this model accurately represents the really endocrine system. Understanding the mechanism underlying glucose-insulin oscillations and determination of the origin of the glucoseinsulin levels oscillations is another purpose of this model. Other applications for this model also have been explored. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Paperback. Bookseller Inventory # 9783639103250

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Book Description VDM Verlag Nov 2008, 2008. Taschenbuch. Book Condition: Neu. This item is printed on demand - Print on Demand Neuware - Diabetes mellitus is a disease in the glucose-insulin 156 pp. Deutsch. Bookseller Inventory # 9783639103250

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