Though the reductionist approachto biology and medicine has led to several imp- tant advances, further progresses with respect to the remaining challenges require integration of representation, characterization and modeling of the studied systems along a wide range of spatial and time scales. Such an approach, intrinsically - lated to systems biology, is poised to ultimately turning biology into a more precise and synthetic discipline, paving the way to extensive preventive and regenerative medicine , drug discovery  and treatment optimization . A particularly appealing and effective approach to addressing the complexity of interactions inherent to the biological systems is provided by the new area of c- plex networks [34, 30, 8, 13, 12]. Basically, it is an extension of graph theory , focusing on the modeling, representation, characterization, analysis and simulation ofcomplexsystemsbyconsideringmanyelementsandtheirinterconnections.C- plex networks concepts and methods have been used to study disease , tr- scription networks [5, 6, 4], protein-protein networks [22, 36, 16, 39], metabolic networks  and anatomy .
"synopsis" may belong to another edition of this title.
We live in a networked world. People are getting more and more interconnected through the new information and communication technologies, like mobile phones and the Internet.
The function of cells can be understood via networks of interacting proteins. Ecosystems can be described through networks of taxonomic relationships between species. The network representation has proved to be a powerful tool to understand the structure and the dynamics of complex systems. Since the pioneering discovery of the scale-free property of the World Wide Web by Albert, Jeong and Barabási, the study of complex networks has become the leading discipline in complexity science.
This volume is intended to bring to the attention of the scientific community recent advances in complex networks. It covers significant aspects of networks' structure and dynamics, both from the analytical and the empirical point of view. The works of this collection are contributed by a truly interdisciplinary community of scientists, from physicists to mathematicians, from computer scientists to engineers and economists.
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