Pentamycin - a new option for the treatment of infections with Trichomonas vaginalis? (German Edition)

 
9783656145516: Pentamycin - a new option for the treatment of infections with Trichomonas vaginalis? (German Edition)
View all copies of this ISBN edition:
 
 

Diplomarbeit aus dem Jahr 2011 im Fachbereich Biologie - Mikrobiologie, Molekularbiologie, Note: 1, Universitšt Wien, Sprache: Deutsch, Abstract: The protozoan parasite Trichomonas vaginalis is the causative agent of trichomonosis which is - with more than 170 million new cases each year - the most prevalent non-viral sexually transmitted disease (STD) worldwide. Although trichomonosis is not a primarily lethal disease, the clinical picture can include severe urogenital inflammations. Chronic infections have been associated with cervical/prostate cancer and a predisposition of HIV infections. In case of pregnancy, chronic infections can also lead to preterm delivery and low birth weight. For more than 50 years, metronidazole, a nitroimidazole antibiotic, has been in use for the treatment of trichomonosis. It is applied orally and although it is mostly compliant, it can have serious side effects. It is also not applicable for pregnant women due to its ability to pass the placenta. Furthermore, an increasing number of emerging metronidazoleresistant T. vaginalis strains has lead to more treatment failures in the last few years. To this day, however, there is no effective alternative drug against trichomonosis available. Pentamycin is a polyene antimycotic and has been in use in the treatment of candidiasis, in preliminary studies it also turned out to be effective against trichomonads. The aim of this study was to evaluate the efficacy of pentamycin against T. vaginalis and the ability to develop resistances in vitro. For these purposes, the dose-effect relationship between pentamycin and four differently metronidazole-sensitive T. vaginalis strains was investigated. Moreover, the protein composition before and after the treatment was compared. To induce resistance, strains were treated with sublethal concentrations of pentamycin within a time of six months. It could be shown that pentamycin is highly effective against T. vaginalis. A 100% eradication of trichomonads

"synopsis" may belong to another edition of this title.

Top Search Results from the AbeBooks Marketplace

1.

Markus Kranzler
Published by Grin Publishing (2012)
ISBN 10: 3656145512 ISBN 13: 9783656145516
New Quantity Available: > 20
Print on Demand
Seller:
Pbshop
(Wood Dale, IL, U.S.A.)
Rating
[?]

Book Description Grin Publishing, 2012. PAP. Condition: New. New Book. Shipped from US within 10 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Seller Inventory # IQ-9783656145516

More information about this seller | Contact this seller

Buy New
US$ 49.67
Convert currency

Add to Basket

Shipping: US$ 3.99
Within U.S.A.
Destination, rates & speeds

2.

Markus Kranzler
Published by Grin Publishing (2012)
ISBN 10: 3656145512 ISBN 13: 9783656145516
New Quantity Available: > 20
Print on Demand
Seller:
Books2Anywhere
(Fairford, GLOS, United Kingdom)
Rating
[?]

Book Description Grin Publishing, 2012. PAP. Condition: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Seller Inventory # IQ-9783656145516

More information about this seller | Contact this seller

Buy New
US$ 49.47
Convert currency

Add to Basket

Shipping: US$ 11.45
From United Kingdom to U.S.A.
Destination, rates & speeds

3.

Markus Kranzler
Published by GRIN Publishing (2012)
ISBN 10: 3656145512 ISBN 13: 9783656145516
New Softcover Quantity Available: 15
Print on Demand
Seller:
Rating
[?]

Book Description GRIN Publishing, 2012. Condition: New. This item is printed on demand for shipment within 3 working days. Seller Inventory # LP9783656145516

More information about this seller | Contact this seller

Buy New
US$ 58.42
Convert currency

Add to Basket

Shipping: US$ 3.12
From Germany to U.S.A.
Destination, rates & speeds

4.

Kranzler, Markus
Published by GRIN Publishing (2016)
ISBN 10: 3656145512 ISBN 13: 9783656145516
New Paperback Quantity Available: 1
Print on Demand
Seller:
Ria Christie Collections
(Uxbridge, United Kingdom)
Rating
[?]

Book Description GRIN Publishing, 2016. Paperback. Condition: New. PRINT ON DEMAND Book; New; Publication Year 2016; Not Signed; Fast Shipping from the UK. No. book. Seller Inventory # ria9783656145516_lsuk

More information about this seller | Contact this seller

Buy New
US$ 60.23
Convert currency

Add to Basket

Shipping: US$ 4.92
From United Kingdom to U.S.A.
Destination, rates & speeds

5.

Markus Kranzler
Published by Grin Verlag
ISBN 10: 3656145512 ISBN 13: 9783656145516
New Paperback Quantity Available: > 20
Seller:
BuySomeBooks
(Las Vegas, NV, U.S.A.)
Rating
[?]

Book Description Grin Verlag. Paperback. Condition: New. 190 pages. Dimensions: 8.3in. x 5.8in. x 0.4in.Diplomarbeit aus dem Jahr 2011 im Fachbereich Biologie - Mikrobiologie, Molekularbiologie, Note: 1, Universitt Wien, Sprache: Deutsch, Abstract: The protozoan parasite Trichomonas vaginalis is the causative agent of trichomonosis which is - with more than 170 million new cases each year - the most prevalent non-viral sexually transmitted disease (STD) worldwide. Although trichomonosis is not a primarily lethal disease, the clinical picture can include severe urogenital inflammations. Chronic infections have been associated with cervicalprostate cancer and a predisposition of HIV infections. In case of pregnancy, chronic infections can also lead to preterm delivery and low birth weight. For more than 50 years, metronidazole, a nitroimidazole antibiotic, has been in use for the treatment of trichomonosis. It is applied orally and although it is mostly compliant, it can have serious side effects. It is also not applicable for pregnant women due to its ability to pass the placenta. Furthermore, an increasing number of emerging metronidazoleresistant T. vaginalis strains has lead to more treatment failures in the last few years. To this day, however, there is no effective alternative drug against trichomonosis available. Pentamycin is a polyene antimycotic and has been in use in the treatment of candidiasis, in preliminary studies it also turned out to be effective against trichomonads. The aim of this study was to evaluate the efficacy of pentamycin against T. vaginalis and the ability to develop resistances in vitro. For these purposes, the dose-effect relationship between pentamycin and four differently metronidazole-sensitive T. vaginalis strains was investigated. Moreover, the protein composition before and after the treatment was compared. To induce resistance, strains were treated with sublethal concentrations of pentamycin within a time of six months. It could be shown that pentamycin is highly effective against T. vaginalis. A 100 eradication of trichomonads This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Paperback. Seller Inventory # 9783656145516

More information about this seller | Contact this seller

Buy New
US$ 66.32
Convert currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, rates & speeds

6.

Markus Kranzler
Published by GRIN Publishing (2012)
ISBN 10: 3656145512 ISBN 13: 9783656145516
New Paperback First Edition Quantity Available: 10
Print on Demand
Seller:
The Book Depository EURO
(London, United Kingdom)
Rating
[?]

Book Description GRIN Publishing, 2012. Paperback. Condition: New. 1. Auflage.. Language: German . Brand New Book ***** Print on Demand *****.Diplomarbeit aus dem Jahr 2011 im Fachbereich Biologie - Mikrobiologie, Molekularbiologie, Note: 1, Universitat Wien, Sprache: Deutsch, Abstract: The protozoan parasite Trichomonas vaginalis is the causative agent of trichomonosis which is - with more than 170 million new cases each year - the most prevalent non-viral sexually transmitted disease (STD) worldwide. Although trichomonosis is not a primarily lethal disease, the clinical picture can include severe urogenital inflammations. Chronic infections have been associated with cervical/prostate cancer and a predisposition of HIV infections. In case of pregnancy, chronic infections can also lead to preterm delivery and low birth weight. For more than 50 years, metronidazole, a nitroimidazole antibiotic, has been in use for the treatment of trichomonosis. It is applied orally and although it is mostly compliant, it can have serious side effects. It is also not applicable for pregnant women due to its ability to pass the placenta. Furthermore, an increasing number of emerging metronidazoleresistant T. vaginalis strains has lead to more treatment failures in the last few years. To this day, however, there is no effective alternative drug against trichomonosis available. Pentamycin is a polyene antimycotic and has been in use in the treatment of candidiasis, in preliminary studies it also turned out to be effective against trichomonads. The aim of this study was to evaluate the efficacy of pentamycin against T. vaginalis and the ability to develop resistances in vitro. For these purposes, the dose-effect relationship between pentamycin and four differently metronidazole-sensitive T. vaginalis strains was investigated. Moreover, the protein composition before and after the treatment was compared. To induce resistance, strains were treated with sublethal concentrations of pentamycin within a time of six months. It could be shown that pentamycin is highly effective against T. vaginalis. A 100 eradication of trichomonads. Seller Inventory # APC9783656145516

More information about this seller | Contact this seller

Buy New
US$ 98.45
Convert currency

Add to Basket

Shipping: US$ 3.81
From United Kingdom to U.S.A.
Destination, rates & speeds