Pharmacokinetic / Pharmacodynamic (PK/PD) Modelling: Pharmacokinetic / Pharmacodynamic (PK/PD) Modelling- with a pre-clinical application

 
9783659129186: Pharmacokinetic / Pharmacodynamic (PK/PD) Modelling: Pharmacokinetic / Pharmacodynamic (PK/PD) Modelling- with a pre-clinical application
View all copies of this ISBN edition:
 
 

Pharmacokinetic-Pharmacodynamic (PK/PD) modeling is scientific mathematical tool which integrates relationship PK model to that of PD model and a statistical model (particularly, the intra- and inter-individual variability of PK and/or PD origin). PK-PD approach is used from initial preclinical stage to last clinical phases for exploring the concentration-effect relationships executed using various approaches, such as steady state concentrations versus non-steady state concentrations models and parametric versus nonparametric models. Basing on the concentration-response invariant data basic models such as fixed-effect, linear, log-linear, Emax and sigmaoid Emax models are used. But in case of time-concentration and time-response variant conditions effect compartment, acute tolerance, sensitization and physiological indirect response models have been used. PK/PD modeling can be used as an applied science tool to provide answers on efficacy and safety of new drugs faster and at a lower cost. Still limits of PK/PD approaches include the development of appropriate models, the validity of surrogate endpoints, and the acceptance of these models in a regulatory environment.

"synopsis" may belong to another edition of this title.

About the Author:

Mr. Dheeraj Gopu has obtained his Master's degree with Pharmacology specialization from Kakatiya University, Warangal, India. He specializes in Pharmacokinetic/Pharmacodynamic modeling of various classes of drugs. Presently he is working as a Assistant Professor in the Department of Pharmacology in Vaagdevi College of Pharmacy, K.U. Warangal, India

"About this title" may belong to another edition of this title.

List Price: US$ 61.00
US$ 46.00

Convert currency

Shipping: US$ 6.42
From United Kingdom to U.S.A.

Destination, rates & speeds

Add to Basket

Top Search Results from the AbeBooks Marketplace

1.

Gopu, Dheeraj
Published by Omniscriptum Gmbh & Co. Kg. 2012-05-29 (2012)
ISBN 10: 3659129186 ISBN 13: 9783659129186
New paperback Quantity Available: > 20
Seller:
Blackwell's
(Oxford, OX, United Kingdom)

Book Description Omniscriptum Gmbh & Co. Kg. 2012-05-29, 2012. paperback. Condition: New. Seller Inventory # 9783659129186

More information about this seller | Contact this seller

Buy New
US$ 46.00
Convert currency

Add to Basket

Shipping: US$ 6.42
From United Kingdom to U.S.A.
Destination, rates & speeds

2.

Gopu, Dheeraj
Published by LAP Lambert Academic Publishing (2017)
ISBN 10: 3659129186 ISBN 13: 9783659129186
New Paperback Quantity Available: 10
Print on Demand
Seller:
Ria Christie Collections
(Uxbridge, United Kingdom)

Book Description LAP Lambert Academic Publishing, 2017. Paperback. Condition: New. PRINT ON DEMAND Book; New; Publication Year 2017; Not Signed; Fast Shipping from the UK. No. book. Seller Inventory # ria9783659129186_lsuk

More information about this seller | Contact this seller

Buy New
US$ 53.33
Convert currency

Add to Basket

Shipping: US$ 4.98
From United Kingdom to U.S.A.
Destination, rates & speeds

3.

Gopu, Dheeraj
Published by LAP Lambert Academic Publishing (2012)
ISBN 10: 3659129186 ISBN 13: 9783659129186
New Quantity Available: > 20
Print on Demand
Seller:
Books2Anywhere
(Fairford, GLOS, United Kingdom)

Book Description LAP Lambert Academic Publishing, 2012. PAP. Condition: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Seller Inventory # LQ-9783659129186

More information about this seller | Contact this seller

Buy New
US$ 53.20
Convert currency

Add to Basket

Shipping: US$ 6.43
From United Kingdom to U.S.A.
Destination, rates & speeds

4.

Gopu, Dheeraj
Published by LAP Lambert Academic Publishing (2012)
ISBN 10: 3659129186 ISBN 13: 9783659129186
New Quantity Available: > 20
Print on Demand
Seller:
Paperbackshop-US
(Wood Dale, IL, U.S.A.)

Book Description LAP Lambert Academic Publishing, 2012. PAP. Condition: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000. Seller Inventory # LQ-9783659129186

More information about this seller | Contact this seller

Buy New
US$ 61.59
Convert currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, rates & speeds

5.

Dheeraj Gopu
Published by LAP Lambert Academic Publishing Jun 2012 (2012)
ISBN 10: 3659129186 ISBN 13: 9783659129186
New Taschenbuch Quantity Available: 1
Seller:
Rheinberg-Buch
(Bergisch Gladbach, Germany)

Book Description LAP Lambert Academic Publishing Jun 2012, 2012. Taschenbuch. Condition: Neu. Neuware - Pharmacokinetic-Pharmacodynamic (PK/PD) modeling is scientific mathematical tool which integrates relationship PK model to that of PD model and a statistical model (particularly, the intra- and inter-individual variability of PK and/or PD origin). PK-PD approach is used from initial preclinical stage to last clinical phases for exploring the concentration-effect relationships executed using various approaches, such as steady state concentrations versus non-steady state concentrations models and parametric versus nonparametric models. Basing on the concentration-response invariant data basic models such as fixed-effect, linear, log-linear, Emax and sigmaoid Emax models are used. But in case of time-concentration and time-response variant conditions effect compartment, acute tolerance, sensitization and physiological indirect response models have been used. PK/PD modeling can be used as an applied science tool to provide answers on efficacy and safety of new drugs faster and at a lower cost. Still limits of PK/PD approaches include the development of appropriate models, the validity of surrogate endpoints, and the acceptance of these models in a regulatory environment. 92 pp. Englisch. Seller Inventory # 9783659129186

More information about this seller | Contact this seller

Buy New
US$ 56.15
Convert currency

Add to Basket

Shipping: US$ 19.06
From Germany to U.S.A.
Destination, rates & speeds

6.

Dheeraj Gopu
Published by LAP Lambert Academic Publishing Jun 2012 (2012)
ISBN 10: 3659129186 ISBN 13: 9783659129186
New Taschenbuch Quantity Available: 1
Seller:
BuchWeltWeit Inh. Ludwig Meier e.K.
(Bergisch Gladbach, Germany)

Book Description LAP Lambert Academic Publishing Jun 2012, 2012. Taschenbuch. Condition: Neu. Neuware - Pharmacokinetic-Pharmacodynamic (PK/PD) modeling is scientific mathematical tool which integrates relationship PK model to that of PD model and a statistical model (particularly, the intra- and inter-individual variability of PK and/or PD origin). PK-PD approach is used from initial preclinical stage to last clinical phases for exploring the concentration-effect relationships executed using various approaches, such as steady state concentrations versus non-steady state concentrations models and parametric versus nonparametric models. Basing on the concentration-response invariant data basic models such as fixed-effect, linear, log-linear, Emax and sigmaoid Emax models are used. But in case of time-concentration and time-response variant conditions effect compartment, acute tolerance, sensitization and physiological indirect response models have been used. PK/PD modeling can be used as an applied science tool to provide answers on efficacy and safety of new drugs faster and at a lower cost. Still limits of PK/PD approaches include the development of appropriate models, the validity of surrogate endpoints, and the acceptance of these models in a regulatory environment. 92 pp. Englisch. Seller Inventory # 9783659129186

More information about this seller | Contact this seller

Buy New
US$ 56.15
Convert currency

Add to Basket

Shipping: US$ 19.06
From Germany to U.S.A.
Destination, rates & speeds

7.

Dheeraj Gopu
Published by LAP Lambert Academic Publishing, Germany (2012)
ISBN 10: 3659129186 ISBN 13: 9783659129186
New Paperback Quantity Available: 10
Print on Demand
Seller:
The Book Depository EURO
(London, United Kingdom)

Book Description LAP Lambert Academic Publishing, Germany, 2012. Paperback. Condition: New. Aufl. Language: English . Brand New Book ***** Print on Demand *****.Pharmacokinetic-Pharmacodynamic (PK/PD) modeling is scientific mathematical tool which integrates relationship PK model to that of PD model and a statistical model (particularly, the intra- and inter-individual variability of PK and/or PD origin). PK-PD approach is used from initial preclinical stage to last clinical phases for exploring the concentration-effect relationships executed using various approaches, such as steady state concentrations versus non-steady state concentrations models and parametric versus nonparametric models. Basing on the concentration-response invariant data basic models such as fixed-effect, linear, log-linear, Emax and sigmaoid Emax models are used. But in case of time-concentration and time-response variant conditions effect compartment, acute tolerance, sensitization and physiological indirect response models have been used. PK/PD modeling can be used as an applied science tool to provide answers on efficacy and safety of new drugs faster and at a lower cost. Still limits of PK/PD approaches include the development of appropriate models, the validity of surrogate endpoints, and the acceptance of these models in a regulatory environment. Seller Inventory # AAV9783659129186

More information about this seller | Contact this seller

Buy New
US$ 83.12
Convert currency

Add to Basket

Shipping: US$ 3.86
From United Kingdom to U.S.A.
Destination, rates & speeds

8.

Gopu, Dheeraj
Published by LAP LAMBERT Academic Publishing
ISBN 10: 3659129186 ISBN 13: 9783659129186
New PAPERBACK Quantity Available: > 20
Seller:
Russell Books
(Victoria, BC, Canada)

Book Description LAP LAMBERT Academic Publishing. PAPERBACK. Condition: New. 3659129186 Special order direct from the distributor. Seller Inventory # ING9783659129186

More information about this seller | Contact this seller

Buy New
US$ 86.93
Convert currency

Add to Basket

Shipping: US$ 6.99
From Canada to U.S.A.
Destination, rates & speeds

9.

Dheeraj Gopu
Published by LAP Lambert Academic Publishing Jun 2012 (2012)
ISBN 10: 3659129186 ISBN 13: 9783659129186
New Taschenbuch Quantity Available: 1
Print on Demand
Seller:
AHA-BUCH GmbH
(Einbeck, Germany)

Book Description LAP Lambert Academic Publishing Jun 2012, 2012. Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Neuware - Pharmacokinetic-Pharmacodynamic (PK/PD) modeling is scientific mathematical tool which integrates relationship PK model to that of PD model and a statistical model (particularly, the intra- and inter-individual variability of PK and/or PD origin). PK-PD approach is used from initial preclinical stage to last clinical phases for exploring the concentration-effect relationships executed using various approaches, such as steady state concentrations versus non-steady state concentrations models and parametric versus nonparametric models. Basing on the concentration-response invariant data basic models such as fixed-effect, linear, log-linear, Emax and sigmaoid Emax models are used. But in case of time-concentration and time-response variant conditions effect compartment, acute tolerance, sensitization and physiological indirect response models have been used. PK/PD modeling can be used as an applied science tool to provide answers on efficacy and safety of new drugs faster and at a lower cost. Still limits of PK/PD approaches include the development of appropriate models, the validity of surrogate endpoints, and the acceptance of these models in a regulatory environment. 92 pp. Englisch. Seller Inventory # 9783659129186

More information about this seller | Contact this seller

Buy New
US$ 56.15
Convert currency

Add to Basket

Shipping: US$ 38.38
From Germany to U.S.A.
Destination, rates & speeds

10.

Dheeraj Gopu
Published by LAP LAMBERT Academic Publishing (2012)
ISBN 10: 3659129186 ISBN 13: 9783659129186
New Paperback Quantity Available: 1
Seller:
Books Express
(Portsmouth, NH, U.S.A.)

Book Description LAP LAMBERT Academic Publishing, 2012. Paperback. Condition: New. Ships with Tracking Number! INTERNATIONAL WORLDWIDE Shipping available. Buy with confidence, excellent customer service!. Seller Inventory # 3659129186n

More information about this seller | Contact this seller

Buy New
US$ 204.30
Convert currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, rates & speeds