Bilayer tablet of Metoprolol tartrate and Hydrochlorthiazide: A novel approach for Bilayer tablet Formulation and Evaluation

 
9783659186684: Bilayer tablet of Metoprolol tartrate and Hydrochlorthiazide: A novel approach for Bilayer tablet Formulation and Evaluation

The main goal of present study was to formulate and invitro evaluate bilayer tablets of Metoprolol tartrate and Hydrochlorothiazide. In this tablet hydrochlorothiazide was formulated as immediate release for which sodium starch glycolate and croscarmellose sodium was used as superdisintegrants. While metoprolol tartrate was formulated as sustained release for which HPMC K4 M and Eudragit RSPO were used as release retarding polymers. In this bilayer tablet hydrochlorothiazide showed quick action and the sustained release of metoprolol tartrate maintain the drug concentration within therapeutic range for period of 12 hrs. Prepared tablets were evaluated for thickness, hardness, friability, uniformity of weight, disintegration time and dissolution study. Disintegration time and drug release were taken as the basis to optimize the tablets.

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About the Author:

Mr. Uttam Nalawade and Mr.Ratnadeep Ghadage have obtained M.Pharmacy degree from Shivaji University, Kolhapur, [M.S.]-India. Their Academic profile is excellent and expertise in pharmaceutical sciences. They are author of several articles published in reputed international journals. Dr. Shriniwas Mohite is Vice-Principal in the RCP, Kasegaon.

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Book Description Book Condition: New. Publisher/Verlag: LAP Lambert Academic Publishing | A novel approach for Bilayer tablet Formulation and Evaluation | The main goal of present study was to formulate and invitro evaluate bilayer tablets of Metoprolol tartrate and Hydrochlorothiazide. In this tablet hydrochlorothiazide was formulated as immediate release for which sodium starch glycolate and croscarmellose sodium was used as superdisintegrants. While metoprolol tartrate was formulated as sustained release for which HPMC K4 M and Eudragit RSPO were used as release retarding polymers. In this bilayer tablet hydrochlorothiazide showed quick action and the sustained release of metoprolol tartrate maintain the drug concentration within therapeutic range for period of 12 hrs. Prepared tablets were evaluated for thickness, hardness, friability, uniformity of weight, disintegration time and dissolution study. Disintegration time and drug release were taken as the basis to optimize the tablets. | Format: Paperback | Language/Sprache: english | 120 pp. Bookseller Inventory # K9783659186684

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Book Description LAP Lambert Academic Publishing Aug 2012, 2012. Taschenbuch. Book Condition: Neu. Neuware - The main goal of present study was to formulate and invitro evaluate bilayer tablets of Metoprolol tartrate and Hydrochlorothiazide. In this tablet hydrochlorothiazide was formulated as immediate release for which sodium starch glycolate and croscarmellose sodium was used as superdisintegrants. While metoprolol tartrate was formulated as sustained release for which HPMC K4 M and Eudragit RSPO were used as release retarding polymers. In this bilayer tablet hydrochlorothiazide showed quick action and the sustained release of metoprolol tartrate maintain the drug concentration within therapeutic range for period of 12 hrs. Prepared tablets were evaluated for thickness, hardness, friability, uniformity of weight, disintegration time and dissolution study. Disintegration time and drug release were taken as the basis to optimize the tablets. 120 pp. Englisch. Bookseller Inventory # 9783659186684

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Book Description LAP Lambert Academic Publishing Aug 2012, 2012. Taschenbuch. Book Condition: Neu. Neuware - The main goal of present study was to formulate and invitro evaluate bilayer tablets of Metoprolol tartrate and Hydrochlorothiazide. In this tablet hydrochlorothiazide was formulated as immediate release for which sodium starch glycolate and croscarmellose sodium was used as superdisintegrants. While metoprolol tartrate was formulated as sustained release for which HPMC K4 M and Eudragit RSPO were used as release retarding polymers. In this bilayer tablet hydrochlorothiazide showed quick action and the sustained release of metoprolol tartrate maintain the drug concentration within therapeutic range for period of 12 hrs. Prepared tablets were evaluated for thickness, hardness, friability, uniformity of weight, disintegration time and dissolution study. Disintegration time and drug release were taken as the basis to optimize the tablets. 120 pp. Englisch. Bookseller Inventory # 9783659186684

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Book Description LAP Lambert Academic Publishing. Paperback. Book Condition: New. Paperback. 120 pages. Dimensions: 8.7in. x 5.9in. x 0.3in.The main goal of present study was to formulate and invitro evaluate bilayer tablets of Metoprolol tartrate and Hydrochlorothiazide. In this tablet hydrochlorothiazide was formulated as immediate release for which sodium starch glycolate and croscarmellose sodium was used as superdisintegrants. While metoprolol tartrate was formulated as sustained release for which HPMC K4 M and Eudragit RSPO were used as release retarding polymers. In this bilayer tablet hydrochlorothiazide showed quick action and the sustained release of metoprolol tartrate maintain the drug concentration within therapeutic range for period of 12 hrs. Prepared tablets were evaluated for thickness, hardness, friability, uniformity of weight, disintegration time and dissolution study. Disintegration time and drug release were taken as the basis to optimize the tablets. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Paperback. Bookseller Inventory # 9783659186684

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Book Description LAP Lambert Academic Publishing, Germany, 2012. Paperback. Book Condition: New. Aufl.. Language: English . Brand New Book ***** Print on Demand *****.The main goal of present study was to formulate and invitro evaluate bilayer tablets of Metoprolol tartrate and Hydrochlorothiazide. In this tablet hydrochlorothiazide was formulated as immediate release for which sodium starch glycolate and croscarmellose sodium was used as superdisintegrants. While metoprolol tartrate was formulated as sustained release for which HPMC K4 M and Eudragit RSPO were used as release retarding polymers. In this bilayer tablet hydrochlorothiazide showed quick action and the sustained release of metoprolol tartrate maintain the drug concentration within therapeutic range for period of 12 hrs. Prepared tablets were evaluated for thickness, hardness, friability, uniformity of weight, disintegration time and dissolution study. Disintegration time and drug release were taken as the basis to optimize the tablets. Bookseller Inventory # AAV9783659186684

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