Determination of Venlafaxine hydrochloride by UV spectrophotometry: Development and validation of Venlafaxine Hcl by UV method

 
9783659219962: Determination of Venlafaxine hydrochloride by UV spectrophotometry: Development and validation of Venlafaxine Hcl by UV method

UV Spectrophotometric determination of Venlafaxine Hydrochloride was done by using Distilled water as a solvent to dissolve the drug(pure) with a known concentration (10 µg/ml). λmax was determined which showed maximum absorbance at 224 nm. It obeys Beer’s Lambert’s law by showing linearity at concentration range 2 - 14 µg/ml. By under going the analysis of formulation we concluded that it has maximum active ingredient in solid dosage form tablets of Venlafaxine Hydrochloride. The percentage purity of Venlafaxine Hydrochloride tablets was determined by performing assay and it was found to be 96.09 % w/w. The percentage recovery is observed in the range of 101.5 % w/w which indicates no interference of the excipients present in the tablet formulation. Precision was determined by under going repeatability studies where absorbance was almost same. Intraday precision was performed by taking the absorbance of the same concentration at several times in a day and its % RSD was minimum as per ICH guidelines. Same absorbance was seen for same concentration i.e., 10 µg/ml when observed on different days by which we determined the interday. Stability was kept unchanged up to 5hrs.

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Prof. R. sundaraganapathy is an eminent professor in the field of pharmaceutical analysis and pharmaceutical chemistry for the last two decades. He is having several number of publications in reputed national and international journals. Author is a former senate member of the Tamilnadu Dr. M.G.R Medical university, Chennai, India.

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Book Description Book Condition: New. Publisher/Verlag: LAP Lambert Academic Publishing | Development and validation of Venlafaxine Hcl by UV method | UV Spectrophotometric determination of Venlafaxine Hydrochloride was done by using Distilled water as a solvent to dissolve the drug(pure) with a known concentration (10 µg/ml). max was determined which showed maximum absorbance at 224 nm. It obeys Beer s Lambert s law by showing linearity at concentration range 2 - 14 µg/ml. By under going the analysis of formulation we concluded that it has maximum active ingredient in solid dosage form tablets of Venlafaxine Hydrochloride. The percentage purity of Venlafaxine Hydrochloride tablets was determined by performing assay and it was found to be 96.09 % w/w. The percentage recovery is observed in the range of 101.5 % w/w which indicates no interference of the excipients present in the tablet formulation. Precision was determined by under going repeatability studies where absorbance was almost same. Intraday precision was performed by taking the absorbance of the same concentration at several times in a day and its % RSD was minimum as per ICH guidelines. Same absorbance was seen for same concentration i.e., 10 µg/ml when observed on different days by which we determined the interday. Stability was kept unchanged up to 5hrs. | Format: Paperback | Language/Sprache: english | 60 pp. Bookseller Inventory # K9783659219962

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Book Description LAP Lambert Academic Publishing Aug 2012, 2012. Taschenbuch. Book Condition: Neu. Neuware - UV Spectrophotometric determination of Venlafaxine Hydrochloride was done by using Distilled water as a solvent to dissolve the drug(pure) with a known concentration (10 µg/ml). max was determined which showed maximum absorbance at 224 nm. It obeys Beer s Lambert s law by showing linearity at concentration range 2 - 14 µg/ml. By under going the analysis of formulation we concluded that it has maximum active ingredient in solid dosage form tablets of Venlafaxine Hydrochloride. The percentage purity of Venlafaxine Hydrochloride tablets was determined by performing assay and it was found to be 96.09 % w/w. The percentage recovery is observed in the range of 101.5 % w/w which indicates no interference of the excipients present in the tablet formulation. Precision was determined by under going repeatability studies where absorbance was almost same. Intraday precision was performed by taking the absorbance of the same concentration at several times in a day and its % RSD was minimum as per ICH guidelines. Same absorbance was seen for same concentration i.e., 10 µg/ml when observed on different days by which we determined the interday. Stability was kept unchanged up to 5hrs. 60 pp. Englisch. Bookseller Inventory # 9783659219962

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Book Description LAP Lambert Academic Publishing Aug 2012, 2012. Taschenbuch. Book Condition: Neu. Neuware - UV Spectrophotometric determination of Venlafaxine Hydrochloride was done by using Distilled water as a solvent to dissolve the drug(pure) with a known concentration (10 µg/ml). max was determined which showed maximum absorbance at 224 nm. It obeys Beer s Lambert s law by showing linearity at concentration range 2 - 14 µg/ml. By under going the analysis of formulation we concluded that it has maximum active ingredient in solid dosage form tablets of Venlafaxine Hydrochloride. The percentage purity of Venlafaxine Hydrochloride tablets was determined by performing assay and it was found to be 96.09 % w/w. The percentage recovery is observed in the range of 101.5 % w/w which indicates no interference of the excipients present in the tablet formulation. Precision was determined by under going repeatability studies where absorbance was almost same. Intraday precision was performed by taking the absorbance of the same concentration at several times in a day and its % RSD was minimum as per ICH guidelines. Same absorbance was seen for same concentration i.e., 10 µg/ml when observed on different days by which we determined the interday. Stability was kept unchanged up to 5hrs. 60 pp. Englisch. Bookseller Inventory # 9783659219962

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Book Description LAP Lambert Academic Publishing. Paperback. Book Condition: New. Paperback. 60 pages. Dimensions: 8.7in. x 5.9in. x 0.1in.UV Spectrophotometric determination of Venlafaxine Hydrochloride was done by using Distilled water as a solvent to dissolve the drug(pure) with a known concentration (10 gml). max was determined which showed maximum absorbance at 224 nm. It obeys Beers Lamberts law by showing linearity at concentration range 2 - 14 gml. By under going the analysis of formulation we concluded that it has maximum active ingredient in solid dosage form tablets of Venlafaxine Hydrochloride. The percentage purity of Venlafaxine Hydrochloride tablets was determined by performing assay and it was found to be 96. 09 ww. The percentage recovery is observed in the range of 101. 5 ww which indicates no interference of the excipients present in the tablet formulation. Precision was determined by under going repeatability studies where absorbance was almost same. Intraday precision was performed by taking the absorbance of the same concentration at several times in a day and its RSD was minimum as per ICH guidelines. Same absorbance was seen for same concentration i. e. , 10 gml when observed on different days by which we determined the interday. Stability was kept unchanged up to 5hrs. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Paperback. Bookseller Inventory # 9783659219962

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Book Description LAP Lambert Academic Publishing, Germany, 2012. Paperback. Book Condition: New. Aufl.. Language: English . Brand New Book ***** Print on Demand *****.UV Spectrophotometric determination of Venlafaxine Hydrochloride was done by using Distilled water as a solvent to dissolve the drug(pure) with a known concentration (10 g/ml). max was determined which showed maximum absorbance at 224 nm. It obeys Beer s Lambert s law by showing linearity at concentration range 2 - 14 g/ml. By under going the analysis of formulation we concluded that it has maximum active ingredient in solid dosage form tablets of Venlafaxine Hydrochloride. The percentage purity of Venlafaxine Hydrochloride tablets was determined by performing assay and it was found to be 96.09 w/w. The percentage recovery is observed in the range of 101.5 w/w which indicates no interference of the excipients present in the tablet formulation. Precision was determined by under going repeatability studies where absorbance was almost same. Intraday precision was performed by taking the absorbance of the same concentration at several times in a day and its RSD was minimum as per ICH guidelines. Same absorbance was seen for same concentration i.e., 10 g/ml when observed on different days by which we determined the interday. Stability was kept unchanged up to 5hrs. Bookseller Inventory # AAV9783659219962

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Book Description LAP Lambert Academic Publishing Aug 2012, 2012. Taschenbuch. Book Condition: Neu. This item is printed on demand - Print on Demand Neuware - UV Spectrophotometric determination of Venlafaxine Hydrochloride was done by using Distilled water as a solvent to dissolve the drug(pure) with a known concentration (10 µg/ml). max was determined which showed maximum absorbance at 224 nm. It obeys Beer s Lambert s law by showing linearity at concentration range 2 - 14 µg/ml. By under going the analysis of formulation we concluded that it has maximum active ingredient in solid dosage form tablets of Venlafaxine Hydrochloride. The percentage purity of Venlafaxine Hydrochloride tablets was determined by performing assay and it was found to be 96.09 % w/w. The percentage recovery is observed in the range of 101.5 % w/w which indicates no interference of the excipients present in the tablet formulation. Precision was determined by under going repeatability studies where absorbance was almost same. Intraday precision was performed by taking the absorbance of the same concentration at several times in a day and its % RSD was minimum as per ICH guidelines. Same absorbance was seen for same concentration i.e., 10 µg/ml when observed on different days by which we determined the interday. Stability was kept unchanged up to 5hrs. 60 pp. Englisch. Bookseller Inventory # 9783659219962

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