ESBL Producing E. coli Isolated from Urinary Tract Infected Patients: Antibiotic susceptibility among Uropathogenic E. coli (UPEC)

 
9783659230394: ESBL Producing E. coli Isolated from Urinary Tract Infected Patients: Antibiotic susceptibility among Uropathogenic E. coli (UPEC)
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Escherichia coli are responsible for up to 80% of urinary tract infections (UTI). It is an example of one such bacterial manifestation that is severely complicated by the emergence of extended spectrum beta-lactamases (ESBLs). ESBL producers are found to be associated with increased morbidity and mortality, especially amongst in- patients in intensive care units. Accurate laboratory detection is important to avoid clinical failure due to inappropriate antimicrobial therapy. These plasmid mediated enzymes mostly evolved via point mutations of the classical TEM-1 and CTX-M β-lactamases but other groups are increasingly prominent, notably the CTX-M types, which evolved via the escape and mutation of chromosomal β-lactamases from Kluyvera spp. In this study antibiotic susceptibility analysis was performed using Kirby Bauer disk diffusion method and phenotypic identification for ESBL production was confirmed by phenotypic confirmatory double disk test (PCDDT) following CLSI guidelines. Multiplex PCR for blaCTX-M and blaTEM was performed on the UPEC isolates. 33.33% of total strains expressed blaTEM & blaCTX-M genes individually and 14.28% expressed both genes respectively.

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About the Author:

Shovan Dutta, MS in Medical Biotechnology, Calcutta School of Tropical Medicine, Kolkata, India. His major research area comprises Urinary Tract Infections (UTI), Cervical Cancer, human leukemic cell line, Species Diversity.

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Book Description Condition: New. Publisher/Verlag: LAP Lambert Academic Publishing | Antibiotic susceptibility among Uropathogenic E. coli (UPEC) | Escherichia coli are responsible for up to 80% of urinary tract infections (UTI). It is an example of one such bacterial manifestation that is severely complicated by the emergence of extended spectrum beta-lactamases (ESBLs). ESBL producers are found to be associated with increased morbidity and mortality, especially amongst in- patients in intensive care units. Accurate laboratory detection is important to avoid clinical failure due to inappropriate antimicrobial therapy. These plasmid mediated enzymes mostly evolved via point mutations of the classical TEM-1 and CTX-M -lactamases but other groups are increasingly prominent, notably the CTX-M types, which evolved via the escape and mutation of chromosomal -lactamases from Kluyvera spp. In this study antibiotic susceptibility analysis was performed using Kirby Bauer disk diffusion method and phenotypic identification for ESBL production was confirmed by phenotypic confirmatory double disk test (PCDDT) following CLSI guidelines. Multiplex PCR for blaCTX-M and blaTEM was performed on the UPEC isolates. 33.33% of total strains expressed blaTEM & blaCTX-M genes individually and 14.28% expressed both genes respectively. | Format: Paperback | Language/Sprache: english | 114 gr | 220x150x4 mm | 64 pp. Seller Inventory # K9783659230394

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Book Description LAP Lambert Academic Publishing Apr 2013, 2013. Taschenbuch. Condition: Neu. Neuware - Escherichia coli are responsible for up to 80% of urinary tract infections (UTI). It is an example of one such bacterial manifestation that is severely complicated by the emergence of extended spectrum beta-lactamases (ESBLs). ESBL producers are found to be associated with increased morbidity and mortality, especially amongst in- patients in intensive care units. Accurate laboratory detection is important to avoid clinical failure due to inappropriate antimicrobial therapy. These plasmid mediated enzymes mostly evolved via point mutations of the classical TEM-1 and CTX-M -lactamases but other groups are increasingly prominent, notably the CTX-M types, which evolved via the escape and mutation of chromosomal -lactamases from Kluyvera spp. In this study antibiotic susceptibility analysis was performed using Kirby Bauer disk diffusion method and phenotypic identification for ESBL production was confirmed by phenotypic confirmatory double disk test (PCDDT) following CLSI guidelines. Multiplex PCR for blaCTX-M and blaTEM was performed on the UPEC isolates. 33.33% of total strains expressed blaTEM & blaCTX-M genes individually and 14.28% expressed both genes respectively. 64 pp. Englisch. Seller Inventory # 9783659230394

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Book Description LAP Lambert Academic Publishing Apr 2013, 2013. Taschenbuch. Condition: Neu. Neuware - Escherichia coli are responsible for up to 80% of urinary tract infections (UTI). It is an example of one such bacterial manifestation that is severely complicated by the emergence of extended spectrum beta-lactamases (ESBLs). ESBL producers are found to be associated with increased morbidity and mortality, especially amongst in- patients in intensive care units. Accurate laboratory detection is important to avoid clinical failure due to inappropriate antimicrobial therapy. These plasmid mediated enzymes mostly evolved via point mutations of the classical TEM-1 and CTX-M -lactamases but other groups are increasingly prominent, notably the CTX-M types, which evolved via the escape and mutation of chromosomal -lactamases from Kluyvera spp. In this study antibiotic susceptibility analysis was performed using Kirby Bauer disk diffusion method and phenotypic identification for ESBL production was confirmed by phenotypic confirmatory double disk test (PCDDT) following CLSI guidelines. Multiplex PCR for blaCTX-M and blaTEM was performed on the UPEC isolates. 33.33% of total strains expressed blaTEM & blaCTX-M genes individually and 14.28% expressed both genes respectively. 64 pp. Englisch. Seller Inventory # 9783659230394

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Book Description LAP Lambert Academic Publishing. Paperback. Condition: New. 64 pages. Dimensions: 8.7in. x 5.9in. x 0.1in.Escherichia coli are responsible for up to 80 of urinary tract infections (UTI). It is an example of one such bacterial manifestation that is severely complicated by the emergence of extended spectrum beta-lactamases (ESBLs). ESBL producers are found to be associated with increased morbidity and mortality, especially amongst in- patients in intensive care units. Accurate laboratory detection is important to avoid clinical failure due to inappropriate antimicrobial therapy. These plasmid mediated enzymes mostly evolved via point mutations of the classical TEM-1 and CTX-M -lactamases but other groups are increasingly prominent, notably the CTX-M types, which evolved via the escape and mutation of chromosomal -lactamases from Kluyvera spp. In this study antibiotic susceptibility analysis was performed using Kirby Bauer disk diffusion method and phenotypic identification for ESBL production was confirmed by phenotypic confirmatory double disk test (PCDDT) following CLSI guidelines. Multiplex PCR for blaCTX-M and blaTEM was performed on the UPEC isolates. 33. 33 of total strains expressed blaTEM and blaCTX-M genes individually and 14. 28 expressed both genes respectively. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Paperback. Seller Inventory # 9783659230394

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Book Description LAP Lambert Academic Publishing, United States, 2013. Paperback. Condition: New. Language: English . Brand New Book. Escherichia coli are responsible for up to 80 of urinary tract infections (UTI). It is an example of one such bacterial manifestation that is severely complicated by the emergence of extended spectrum beta-lactamases (ESBLs). ESBL producers are found to be associated with increased morbidity and mortality, especially amongst in- patients in intensive care units. Accurate laboratory detection is important to avoid clinical failure due to inappropriate antimicrobial therapy. These plasmid mediated enzymes mostly evolved via point mutations of the classical TEM-1 and CTX-M -lactamases but other groups are increasingly prominent, notably the CTX-M types, which evolved via the escape and mutation of chromosomal -lactamases from Kluyvera spp. In this study antibiotic susceptibility analysis was performed using Kirby Bauer disk diffusion method and phenotypic identification for ESBL production was confirmed by phenotypic confirmatory double disk test (PCDDT) following CLSI guidelines. Multiplex PCR for blaCTX-M and blaTEM was performed on the UPEC isolates. 33.33 of total strains expressed blaTEM blaCTX-M genes individually and 14.28 expressed both genes respectively. Seller Inventory # KNV9783659230394

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Book Description LAP Lambert Academic Publishing Apr 2013, 2013. Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Neuware - Escherichia coli are responsible for up to 80% of urinary tract infections (UTI). It is an example of one such bacterial manifestation that is severely complicated by the emergence of extended spectrum beta-lactamases (ESBLs). ESBL producers are found to be associated with increased morbidity and mortality, especially amongst in- patients in intensive care units. Accurate laboratory detection is important to avoid clinical failure due to inappropriate antimicrobial therapy. These plasmid mediated enzymes mostly evolved via point mutations of the classical TEM-1 and CTX-M -lactamases but other groups are increasingly prominent, notably the CTX-M types, which evolved via the escape and mutation of chromosomal -lactamases from Kluyvera spp. In this study antibiotic susceptibility analysis was performed using Kirby Bauer disk diffusion method and phenotypic identification for ESBL production was confirmed by phenotypic confirmatory double disk test (PCDDT) following CLSI guidelines. Multiplex PCR for blaCTX-M and blaTEM was performed on the UPEC isolates. 33.33% of total strains expressed blaTEM & blaCTX-M genes individually and 14.28% expressed both genes respectively. 64 pp. Englisch. Seller Inventory # 9783659230394

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