Ck - 17 Expression in OSMF: Cytokeratin-17 Expression in Oral Sub mucous Fibrosis An Immunohistochemical Study

 
9783659322983: Ck - 17 Expression in OSMF: Cytokeratin-17 Expression in Oral Sub mucous Fibrosis An Immunohistochemical Study
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Oral submucous fibrosis (OSMF) is characterized by abnormal collagen metabolism in the submucosal connective tissue.Its influence on the overlying epithelium is not known but about 14% of OSMF cases undergo malignant transformation to Squamous cell carcinoma indicating an association with abnormality of the epithelium. Here in our study we have defined the keratin expression profile, by immunohistochemistry and quantitative image analysis, using anti-keratin monoclonal antibody (CK 17) on 30 OSMF samples and on 10 normal mucous membrane samples. The statistical analysis was done using Chi- square test and the p – value was (p < 0.02) was statistically significant.All the normal cases showed moderate staining intensity in the basal layer and mild staining intensity in the suprabasal layer which was different from that of the OSMF cases.When observed with quantitative image analysis OSMF expressed more number of positive cells when compared to that of the normal mucosal.This altered keratinocyte phenotype in OSMF indicates a potential to be used as a surrogate markers of malignant transformation

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I Dr R·Snehalatha Completed Master of Dental Surgery in Oral & Maxillofacilal Pathology,from SAVEETHA UNIVERSITY, CHENNAI. Presently Working as assistant professor at SVS INSTITUTE OF DENTAL SCIENCES,A.P.Won best poster award for Rosai Dorfman Syndrome – A Case report – at the National IAOMP Conference in December 2007.

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Book Description Condition: New. Publisher/Verlag: LAP Lambert Academic Publishing | Cytokeratin-17 Expression in Oral Sub mucous Fibrosis An Immunohistochemical Study | Oral submucous fibrosis (OSMF) is characterized by abnormal collagen metabolism in the submucosal connective tissue.Its influence on the overlying epithelium is not known but about 14% of OSMF cases undergo malignant transformation to Squamous cell carcinoma indicating an association with abnormality of the epithelium. Here in our study we have defined the keratin expression profile, by immunohistochemistry and quantitative image analysis, using anti-keratin monoclonal antibody (CK 17) on 30 OSMF samples and on 10 normal mucous membrane samples. The statistical analysis was done using Chi- square test and the p value was (p &lt; 0.02) was statistically significant.All the normal cases showed moderate staining intensity in the basal layer and mild staining intensity in the suprabasal layer which was different from that of the OSMF cases.When observed with quantitative image analysis OSMF expressed more number of positive cells when compared to that of the normal mucosal.This altered keratinocyte phenotype in OSMF indicates a potential to be used as a surrogate markers of malignant transformation | Format: Paperback | Language/Sprache: english | 203 gr | 220x150x7 mm | 140 pp. Seller Inventory # K9783659322983

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Book Description LAP Lambert Academic Publishing Feb 2013, 2013. Taschenbuch. Condition: Neu. Neuware - Oral submucous fibrosis (OSMF) is characterized by abnormal collagen metabolism in the submucosal connective tissue.Its influence on the overlying epithelium is not known but about 14% of OSMF cases undergo malignant transformation to Squamous cell carcinoma indicating an association with abnormality of the epithelium. Here in our study we have defined the keratin expression profile, by immunohistochemistry and quantitative image analysis, using anti-keratin monoclonal antibody (CK 17) on 30 OSMF samples and on 10 normal mucous membrane samples. The statistical analysis was done using Chi- square test and the p value was (p < 0.02) was statistically significant.All the normal cases showed moderate staining intensity in the basal layer and mild staining intensity in the suprabasal layer which was different from that of the OSMF cases.When observed with quantitative image analysis OSMF expressed more number of positive cells when compared to that of the normal mucosal.This altered keratinocyte phenotype in OSMF indicates a potential to be used as a surrogate markers of malignant transformation 140 pp. Englisch. Seller Inventory # 9783659322983

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Book Description LAP Lambert Academic Publishing Feb 2013, 2013. Taschenbuch. Condition: Neu. Neuware - Oral submucous fibrosis (OSMF) is characterized by abnormal collagen metabolism in the submucosal connective tissue.Its influence on the overlying epithelium is not known but about 14% of OSMF cases undergo malignant transformation to Squamous cell carcinoma indicating an association with abnormality of the epithelium. Here in our study we have defined the keratin expression profile, by immunohistochemistry and quantitative image analysis, using anti-keratin monoclonal antibody (CK 17) on 30 OSMF samples and on 10 normal mucous membrane samples. The statistical analysis was done using Chi- square test and the p value was (p < 0.02) was statistically significant.All the normal cases showed moderate staining intensity in the basal layer and mild staining intensity in the suprabasal layer which was different from that of the OSMF cases.When observed with quantitative image analysis OSMF expressed more number of positive cells when compared to that of the normal mucosal.This altered keratinocyte phenotype in OSMF indicates a potential to be used as a surrogate markers of malignant transformation 140 pp. Englisch. Seller Inventory # 9783659322983

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Book Description LAP Lambert Academic Publishing Feb 2013, 2013. Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Neuware - Oral submucous fibrosis (OSMF) is characterized by abnormal collagen metabolism in the submucosal connective tissue.Its influence on the overlying epithelium is not known but about 14% of OSMF cases undergo malignant transformation to Squamous cell carcinoma indicating an association with abnormality of the epithelium. Here in our study we have defined the keratin expression profile, by immunohistochemistry and quantitative image analysis, using anti-keratin monoclonal antibody (CK 17) on 30 OSMF samples and on 10 normal mucous membrane samples. The statistical analysis was done using Chi- square test and the p value was (p < 0.02) was statistically significant.All the normal cases showed moderate staining intensity in the basal layer and mild staining intensity in the suprabasal layer which was different from that of the OSMF cases.When observed with quantitative image analysis OSMF expressed more number of positive cells when compared to that of the normal mucosal.This altered keratinocyte phenotype in OSMF indicates a potential to be used as a surrogate markers of malignant transformation 140 pp. Englisch. Seller Inventory # 9783659322983

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Book Description LAP Lambert Academic Publishing, United States, 2013. Paperback. Condition: New. Language: English . Brand New Book. Oral submucous fibrosis (OSMF) is characterized by abnormal collagen metabolism in the submucosal connective tissue.Its influence on the overlying epithelium is not known but about 14 of OSMF cases undergo malignant transformation to Squamous cell carcinoma indicating an association with abnormality of the epithelium. Here in our study we have defined the keratin expression profile, by immunohistochemistry and quantitative image analysis, using anti-keratin monoclonal antibody (CK 17) on 30 OSMF samples and on 10 normal mucous membrane samples. The statistical analysis was done using Chi- square test and the p - value was (p. Seller Inventory # KNV9783659322983

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Book Description LAP Lambert Academic Publishing. Paperback. Condition: New. 140 pages. Dimensions: 8.7in. x 5.9in. x 0.3in.Oral submucous fibrosis (OSMF) is characterized by abnormal collagen metabolism in the submucosal connective tissue. Its influence on the overlying epithelium is not known but about 14 of OSMF cases undergo malignant transformation to Squamous cell carcinoma indicating an association with abnormality of the epithelium. Here in our study we have defined the keratin expression profile, by immunohistochemistry and quantitative image analysis, using anti-keratin monoclonal antibody (CK 17) on 30 OSMF samples and on 10 normal mucous membrane samples. The statistical analysis was done using Chi- square test and the p value was (p 0. 02) was statistically significant. All the normal cases showed moderate staining intensity in the basal layer and mild staining intensity in the suprabasal layer which was different from that of the OSMF cases. When observed with quantitative image analysis OSMF expressed more number of positive cells when compared to that of the normal mucosal. This altered keratinocyte phenotype in OSMF indicates a potential to be used as a surrogate markers of malignant transformation This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Paperback. Seller Inventory # 9783659322983

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