Liver Protection by Natural Means: Hepatoprotective agents from Medicinal Plants

 
9783659746291: Liver Protection by Natural Means: Hepatoprotective agents from Medicinal Plants

Due to the high interest in bioactive plant derived materials, hepatoprotective activity of the hydro-alcohol extract of Gentiana spicata (Gentianaceae) on carbon tetrachloride treated rats was investigated. This plant is common in the tropics and subtropics of both hemispheres. It is commonly used as folk medicine for treating stomach disorders, hypertension, renal colic, rheumatic pains, and for elimination of stones from the kidney and the ureters. Pre-treatment with gentiana extract significantly decreased alanine aminotransferase and aspartate aminotransferase enzymes, the major indicators of liver injury. In addition to, the capability of the extract to restore reduced glutathione depletion and to deplete reduced the level of thiobarbituric acid reactive substances. Furthermore, histopathological observation also showed an obvious amelioration in liver cell necrosis, liver lesions, and fatty changes. A new carboxygentisic acid (spicatic acid) was isolated as a first report in this study, besides flavonoids and catechins and their gallolyated derivatives. All structures were elucidated on the basis of conventional analytical methods.

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About the Author:

Dr. Heba Handoussa has a considerable experience in undergraduate teaching as a lecturer of Pharmaceutical Biology at German University in Cairo.In another focus area, she has extensive practice in plant metabolites analysis,mass spectrometers and spectroscopic techniques. Main author and reviewer of several published articles in reputable journals

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Book Description Book Condition: New. Publisher/Verlag: LAP Lambert Academic Publishing | Hepatoprotective agents from Medicinal Plants | Due to the high interest in bioactive plant derived materials, hepatoprotective activity of the hydro-alcohol extract of Gentiana spicata (Gentianaceae) on carbon tetrachloride treated rats was investigated. This plant is common in the tropics and subtropics of both hemispheres. It is commonly used as folk medicine for treating stomach disorders, hypertension, renal colic, rheumatic pains, and for elimination of stones from the kidney and the ureters. Pre-treatment with gentiana extract significantly decreased alanine aminotransferase and aspartate aminotransferase enzymes, the major indicators of liver injury. In addition to, the capability of the extract to restore reduced glutathione depletion and to deplete reduced the level of thiobarbituric acid reactive substances. Furthermore, histopathological observation also showed an obvious amelioration in liver cell necrosis, liver lesions, and fatty changes. A new carboxygentisic acid (spicatic acid) was isolated as a first report in this study, besides flavonoids and catechins and their gallolyated derivatives. All structures were elucidated on the basis of conventional analytical methods. | Format: Paperback | Language/Sprache: english | 132 pp. Bookseller Inventory # K9783659746291

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Book Description LAP Lambert Academic Publishing Sep 2015, 2015. Taschenbuch. Book Condition: Neu. Neuware - Due to the high interest in bioactive plant derived materials, hepatoprotective activity of the hydro-alcohol extract of Gentiana spicata (Gentianaceae) on carbon tetrachloride treated rats was investigated. This plant is common in the tropics and subtropics of both hemispheres. It is commonly used as folk medicine for treating stomach disorders, hypertension, renal colic, rheumatic pains, and for elimination of stones from the kidney and the ureters. Pre-treatment with gentiana extract significantly decreased alanine aminotransferase and aspartate aminotransferase enzymes, the major indicators of liver injury. In addition to, the capability of the extract to restore reduced glutathione depletion and to deplete reduced the level of thiobarbituric acid reactive substances. Furthermore, histopathological observation also showed an obvious amelioration in liver cell necrosis, liver lesions, and fatty changes. A new carboxygentisic acid (spicatic acid) was isolated as a first report in this study, besides flavonoids and catechins and their gallolyated derivatives. All structures were elucidated on the basis of conventional analytical methods. 132 pp. Englisch. Bookseller Inventory # 9783659746291

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Book Description LAP Lambert Academic Publishing Sep 2015, 2015. Taschenbuch. Book Condition: Neu. Neuware - Due to the high interest in bioactive plant derived materials, hepatoprotective activity of the hydro-alcohol extract of Gentiana spicata (Gentianaceae) on carbon tetrachloride treated rats was investigated. This plant is common in the tropics and subtropics of both hemispheres. It is commonly used as folk medicine for treating stomach disorders, hypertension, renal colic, rheumatic pains, and for elimination of stones from the kidney and the ureters. Pre-treatment with gentiana extract significantly decreased alanine aminotransferase and aspartate aminotransferase enzymes, the major indicators of liver injury. In addition to, the capability of the extract to restore reduced glutathione depletion and to deplete reduced the level of thiobarbituric acid reactive substances. Furthermore, histopathological observation also showed an obvious amelioration in liver cell necrosis, liver lesions, and fatty changes. A new carboxygentisic acid (spicatic acid) was isolated as a first report in this study, besides flavonoids and catechins and their gallolyated derivatives. All structures were elucidated on the basis of conventional analytical methods. 132 pp. Englisch. Bookseller Inventory # 9783659746291

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Handoussa Heba, Ayoub Nahla, Mahran Laila
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Book Description LAP Lambert Academic Publishing, United States, 2015. Paperback. Book Condition: New. Language: English . Brand New Book ***** Print on Demand *****.Due to the high interest in bioactive plant derived materials, hepatoprotective activity of the hydro-alcohol extract of Gentiana spicata (Gentianaceae) on carbon tetrachloride treated rats was investigated. This plant is common in the tropics and subtropics of both hemispheres. It is commonly used as folk medicine for treating stomach disorders, hypertension, renal colic, rheumatic pains, and for elimination of stones from the kidney and the ureters. Pre-treatment with gentiana extract significantly decreased alanine aminotransferase and aspartate aminotransferase enzymes, the major indicators of liver injury. In addition to, the capability of the extract to restore reduced glutathione depletion and to deplete reduced the level of thiobarbituric acid reactive substances. Furthermore, histopathological observation also showed an obvious amelioration in liver cell necrosis, liver lesions, and fatty changes. A new carboxygentisic acid (spicatic acid) was isolated as a first report in this study, besides flavonoids and catechins and their gallolyated derivatives. All structures were elucidated on the basis of conventional analytical methods. Bookseller Inventory # AAV9783659746291

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Book Description LAP Lambert Academic Publishing Sep 2015, 2015. Taschenbuch. Book Condition: Neu. This item is printed on demand - Print on Demand Neuware - Due to the high interest in bioactive plant derived materials, hepatoprotective activity of the hydro-alcohol extract of Gentiana spicata (Gentianaceae) on carbon tetrachloride treated rats was investigated. This plant is common in the tropics and subtropics of both hemispheres. It is commonly used as folk medicine for treating stomach disorders, hypertension, renal colic, rheumatic pains, and for elimination of stones from the kidney and the ureters. Pre-treatment with gentiana extract significantly decreased alanine aminotransferase and aspartate aminotransferase enzymes, the major indicators of liver injury. In addition to, the capability of the extract to restore reduced glutathione depletion and to deplete reduced the level of thiobarbituric acid reactive substances. Furthermore, histopathological observation also showed an obvious amelioration in liver cell necrosis, liver lesions, and fatty changes. A new carboxygentisic acid (spicatic acid) was isolated as a first report in this study, besides flavonoids and catechins and their gallolyated derivatives. All structures were elucidated on the basis of conventional analytical methods. 132 pp. Englisch. Bookseller Inventory # 9783659746291

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