Synopsis
Osteoprotegerin is basic glycoprotein that in humans is encoded by the TNFRSF11B gene. It is produced by osteoblasts and other mesenchymal cells, lacks a transmembrane domain and acts as a secreted decoy receptor which is a member of the tumor necrosis factor (TNF) receptor superfamily that has no direct signaling capacity. OPG acts by binding to its natural ligand OPGL, which is also known as RANKL (receptor activator of NF-kappa B ligand). This binding prevents RANKL from activating its cognate receptor RANK, which is the osteoclast receptor vital for osteoclast differentiation, activation and survival. Synthesis of cartilage by chondrocytes is one of the important steps for endochondral bone formation. Osteoprotegerin is critical for bone development and remodeling and has been shown to be required for osteoclast function.
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About the Author
Ranim Mira is a Physician who graduated from Zawia University Medical School, Libya in 2008. She obtained Master of Science (MS) degree in Biochemistry from Rush University Medical center, USA in 2015, Her research focused on musculoskeletal system specifically on chondrocyte development and remodeling.
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Role of Osteoprotegerin in Chondrocyte Development and Remodeling
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LAP Lambert Academic Publishing Nov 2015, 2015
ISBN 10: 3659791164
ISBN 13: 9783659791161
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Osteoprotegerin is basic glycoprotein that in humans is encoded by the TNFRSF11B gene. It is produced by osteoblasts and other mesenchymal cells, lacks a transmembrane domain and acts as a secreted decoy receptor which is a member of the tumor necrosis factor (TNF) receptor superfamily that has no direct signaling capacity. OPG acts by binding to its natural ligand OPGL, which is also known as RANKL (receptor activator of NF-kappa B ligand). This binding prevents RANKL from activating its cognate receptor RANK, which is the osteoclast receptor vital for osteoclast differentiation, activation and survival. Synthesis of cartilage by chondrocytes is one of the important steps for endochondral bone formation. Osteoprotegerin is critical for bone development and remodeling and has been shown to be required for osteoclast function. 68 pp. Englisch. Seller Inventory # 9783659791161
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Role of Osteoprotegerin in Chondrocyte Development and Remodeling
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Mira RanimRanim Mira is a Physician who graduated from Zawia University Medical School, Libya in 2008. She obtained Master of Science (MS) degree in Biochemistry from Rush University Medical center, USA in 2015, Her research focused . Seller Inventory # 159145366
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Role of Osteoprotegerin in Chondrocyte Development and Remodeling
Published by
LAP Lambert Academic Publishing Nov 2015, 2015
ISBN 10: 3659791164
ISBN 13: 9783659791161
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Taschenbuch
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Taschenbuch. Condition: Neu. Neuware -Osteoprotegerin is basic glycoprotein that in humans is encoded by the TNFRSF11B gene. It is produced by osteoblasts and other mesenchymal cells, lacks a transmembrane domain and acts as a secreted decoy receptor which is a member of the tumor necrosis factor (TNF) receptor superfamily that has no direct signaling capacity. OPG acts by binding to its natural ligand OPGL, which is also known as RANKL (receptor activator of NF-kappa B ligand). This binding prevents RANKL from activating its cognate receptor RANK, which is the osteoclast receptor vital for osteoclast differentiation, activation and survival. Synthesis of cartilage by chondrocytes is one of the important steps for endochondral bone formation. Osteoprotegerin is critical for bone development and remodeling and has been shown to be required for osteoclast function.Books on Demand GmbH, Überseering 33, 22297 Hamburg 68 pp. Englisch. Seller Inventory # 9783659791161
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Role of Osteoprotegerin in Chondrocyte Development and Remodeling
Published by
LAP Lambert Academic Publishing, 2015
ISBN 10: 3659791164
ISBN 13: 9783659791161
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Osteoprotegerin is basic glycoprotein that in humans is encoded by the TNFRSF11B gene. It is produced by osteoblasts and other mesenchymal cells, lacks a transmembrane domain and acts as a secreted decoy receptor which is a member of the tumor necrosis factor (TNF) receptor superfamily that has no direct signaling capacity. OPG acts by binding to its natural ligand OPGL, which is also known as RANKL (receptor activator of NF-kappa B ligand). This binding prevents RANKL from activating its cognate receptor RANK, which is the osteoclast receptor vital for osteoclast differentiation, activation and survival. Synthesis of cartilage by chondrocytes is one of the important steps for endochondral bone formation. Osteoprotegerin is critical for bone development and remodeling and has been shown to be required for osteoclast function. Seller Inventory # 9783659791161
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Role of Osteoprotegerin in Chondrocyte Development and Remodeling
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ISBN 10: 3659791164
ISBN 13: 9783659791161
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Taschenbuch. Condition: Neu. Role of Osteoprotegerin in Chondrocyte Development and Remodeling | Ranim Mira | Taschenbuch | 68 S. | Englisch | 2015 | LAP Lambert Academic Publishing | EAN 9783659791161 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu. Seller Inventory # 104096260