Developmental Aspects of the Lymphatic Vascular System (Advances in Anatomy, Embryology and Cell Biology, 214) - Softcover

Softcover

ISBN 10: 3709116457 ISBN 13: 9783709116456

Publisher: Springer, 2013

Synopsis

The book focuses on the lymphatic vascular system from a developmental biologist’s point of view. It provides an overview on the many recent advances in understanding the development of lymphatic vessels, using advanced genetic models in conjunction with state of the art imaging. For each chapter a synopsis is provided, highlighting the main points in a concise manner. The book is intended for professors and researchers in vascular biology, angiogenesis research and developmental biology. It furthermore offers an excellent basis for entry level researchers and newcomers to this field, as well as for teachers, graduate students, advanced science and medical students.

About this title

About the Author

Friedemann Kiefer is group leader at the Max Planck Institute for Molecular Biomedicine in Münster, Germany and Adjunct Professor at the Medical Faculty of the University of Münster. Stefan Schulte-Merker is group leader and Professor of Molecular Developmental Biology at the Hubrecht Institute in Utrecht, The Netherlands.

From the Back Cover

For decades, lymphatic vessels were considered to be of “lesser significance” than blood vessels, and the fundamental importance of lymphatic vessels for physiological tissue homeostasis and their involvement in many pathological processes have only recently been fully appreciated. It is clear by now that all higher vertebrates possess a lymphatic vessel system, and that malfunctioning of the lymphatic vasculature has severe pathophysiological consequences.

Still, many central aspects of the developmental origin, growth control and regulation of lymphatic vessels are not sufficiently understood. This volume of “Advances in Anatomy, Embryology, and Cell Biology” focuses on the lymphatic vascular system from a developmental point of view, presenting exciting recent advances in elucidating the development and molecular control of lymphatic vessels. A collection of focused reviews, written by respected experts, describes ostensively how advanced genetic models and state-of-the-art imaging are being used to decipher the action of transcriptional programs, growth factors and matrix components in the regulation of lymphatic endothelial cell behavior. A synopsis is provided for each chapter, concisely highlighting the main points.

This collection provides both an ideal introduction to lymph vessel biology for newcomers and an invaluable resource for experts.

Edition details

• Publisher: Springer
• Publication date: 2013
• Language: English
• ISBN 10: 3709116457
• ISBN 13: 9783709116456
• Binding: Paperback
• Number of pages: 216
• Editor: Kiefer Friedemann, Schulte-Merker Stefan