Bortezomib in the Treatment of Multiple Myeloma (Milestones in Drug Therapy)

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9783764389475: Bortezomib in the Treatment of Multiple Myeloma (Milestones in Drug Therapy)
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Multiple Myeloma (MM) is the second most common type of blood cancer, resulting from an overproduction of cancerous infection-fighting white blood cells, known as plasma cells. Plasma cells are a crucial part of the immune system responsible for the production of antibodies. Bortezomib is a promising anticancer drug targeting the proteasome. This proteasome inhibitor induces cell stress and apoptosis in the cancer cells. While multiple mechanisms are likely to be involved, proteasome inhibition may prevent the degradation of pro-apoptotic factors, permitting activation of programmed cell death in neoplastic cells dependent upon the suppression of proapoptotic pathways. This monograph on bortezomib is a valuable source of information for researchers and clinicians from the fields of oncology and pharmacology, working either in academia or the pharmaceutical industry.

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Irene M. Ghobrial (editor), Paul G. Richardson (editor), Kenneth C. Anderson (editor)
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Book Description Springer Basel AG Nov 2010, 2010. Buch. Condition: Neu. Neuware - Multiple Myeloma (MM) is the second most-common blood cancer, resulting from overproduction of cancerous infection-fighting white blood cells, known as plasma cells. Plasma cells are a crucial part of the immune system responsible for the production of antibodies. Bortezomib is a promising anticancer-drug targeting the proteasome. This proteasome inhibitor induces cell stress and apoptosis in the cancer cells. While multiple mechanisms are likely to be involved, proteasome inhibition may prevent degradation of pro-apoptotic factors, permitting activation of programmed cell death in neoplastic cells dependent upon suppression of pro-apoptotic pathways.This monograph on bortezomib is a valuable source of information for researchers and clinicians from oncology and pharmacology, working either in academia or the pharmaceutical industry. 179 pp. Englisch. Seller Inventory # 9783764389475

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Book Description Springer Basel AG Nov 2010, 2010. Buch. Condition: Neu. Neuware - Multiple Myeloma (MM) is the second most-common blood cancer, resulting from overproduction of cancerous infection-fighting white blood cells, known as plasma cells. Plasma cells are a crucial part of the immune system responsible for the production of antibodies. Bortezomib is a promising anticancer-drug targeting the proteasome. This proteasome inhibitor induces cell stress and apoptosis in the cancer cells. While multiple mechanisms are likely to be involved, proteasome inhibition may prevent degradation of pro-apoptotic factors, permitting activation of programmed cell death in neoplastic cells dependent upon suppression of pro-apoptotic pathways.This monograph on bortezomib is a valuable source of information for researchers and clinicians from oncology and pharmacology, working either in academia or the pharmaceutical industry. 179 pp. Englisch. Seller Inventory # 9783764389475

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Book Description Springer Basel AG Nov 2010, 2010. Buch. Condition: Neu. Neuware - Multiple Myeloma (MM) is the second most-common blood cancer, resulting from overproduction of cancerous infection-fighting white blood cells, known as plasma cells. Plasma cells are a crucial part of the immune system responsible for the production of antibodies. Bortezomib is a promising anticancer-drug targeting the proteasome. This proteasome inhibitor induces cell stress and apoptosis in the cancer cells. While multiple mechanisms are likely to be involved, proteasome inhibition may prevent degradation of pro-apoptotic factors, permitting activation of programmed cell death in neoplastic cells dependent upon suppression of pro-apoptotic pathways.This monograph on bortezomib is a valuable source of information for researchers and clinicians from oncology and pharmacology, working either in academia or the pharmaceutical industry. 179 pp. Englisch. Seller Inventory # 9783764389475

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Book Description Birkhauser, 2010. Hardcover. Condition: Brand New. 1st edition. edition. 179 pages. 9.29x6.30x0.55 inches. In Stock. Seller Inventory # __3764389478

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