Geometric, Feature- and Graph-based Analysis of Protein Structures: Novel Methods and Computational Analysis - Softcover
Synopsis
The structural comparison of whole proteins or protein binding sites is usually performed by making use of graphs. Even though graphs exhibit a lot of interesting and useful properties, the usage of other representations can come along with several benefits. In this book the representation of a protein binding site is tackled. Three representations are considered namely the geometric, the feature-based and the graph-based representation. For all three types, some completely new algorithms are developed and presented. Moreover, existing methods are adapted to the application of protein binding sites' comparison. In addition, algorithms for the construction of multiple structural alignments are presented as a structural counterpart to multiple sequence alignment. By considering four different types of experiments, namely classification, similarity retrieval, clustering and construction of structural alignments, strengths and weaknesses of the proposed methods are detected and discussed. In addition a hybrid approach is presented which combines the benefits of a feature-based and a geometric method leading to a significant speed-up while still holding very good results.
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About the Author
holds an M.Sc. degree in Computer Science (Dipl.-Inf.) from the Universität Dortmund, Germany, and a Ph.D. degree in the Natural Sciences (Dr. rer. nat.) from the Philipps-Universität Marburg, Germany. Since 2007 he is a research staff member in the Computational Intelligence group at Philipps-Universität Marburg.
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Geometric, Feature- and Graph-based Analysis of Protein Structures
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Südwestdeutscher Verlag Für Hochschulschriften AG Co. KG Jul 2015, 2015
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The structural comparison of whole proteins or protein binding sites is usually performed by making use of graphs. Even though graphs exhibit a lot of interesting and useful properties, the usage of other representations can come along with several benefits. In this book the representation of a protein binding site is tackled. Three representations are considered namely the geometric, the feature-based and the graph-based representation. For all three types, some completely new algorithms are developed and presented. Moreover, existing methods are adapted to the application of protein binding sites' comparison. In addition, algorithms for the construction of multiple structural alignments are presented as a structural counterpart to multiple sequence alignment. By considering four different types of experiments, namely classification, similarity retrieval, clustering and construction of structural alignments, strengths and weaknesses of the proposed methods are detected and discussed. In addition a hybrid approach is presented which combines the benefits of a feature-based and a geometric method leading to a significant speed-up while still holding very good results. 404 pp. Englisch. Seller Inventory # 9783838134796
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Geometric, Feature- and Graph-based Analysis of Protein Structures
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Fober Thomasholds an M.Sc. degree in Computer Science (Dipl.-Inf.) from the Universitaet Dortmund, Germany, and a Ph.D. degree in the Natural Sciences (Dr. rer. nat.) from the Philipps-Universitaet Marburg, Germany. Since 2007 he is a . Seller Inventory # 5407753
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Geometric, Feature- and Graph-based Analysis of Protein Structures | Novel Methods and Computational Analysis
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Taschenbuch. Condition: Neu. Geometric, Feature- and Graph-based Analysis of Protein Structures | Novel Methods and Computational Analysis | Thomas Fober | Taschenbuch | Paperback | 404 S. | Englisch | 2015 | Südwestdeutscher Verlag für Hochschulschriften AG Co. KG | EAN 9783838134796 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu Print on Demand. Seller Inventory # 105689820
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Geometric, Feature- and Graph-based Analysis of Protein Structures
Published by
Südwestdeutscher Verlag Für Hochschulschriften AG Co. KG Jul 2015, 2015
ISBN 10: 3838134796
ISBN 13: 9783838134796
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Taschenbuch. Condition: Neu. Neuware -The structural comparison of whole proteins or protein binding sites is usually performed by making use of graphs. Even though graphs exhibit a lot of interesting and useful properties, the usage of other representations can come along with several benefits. In this book the representation of a protein binding site is tackled. Three representations are considered namely the geometric, the feature-based and the graph-based representation. For all three types, some completely new algorithms are developed and presented. Moreover, existing methods are adapted to the application of protein binding sites' comparison. In addition, algorithms for the construction of multiple structural alignments are presented as a structural counterpart to multiple sequence alignment. By considering four different types of experiments, namely classification, similarity retrieval, clustering and construction of structural alignments, strengths and weaknesses of the proposed methods are detected and discussed. In addition a hybrid approach is presented which combines the benefits of a feature-based and a geometric method leading to a significant speed-up while still holding very good results.Books on Demand GmbH, Überseering 33, 22297 Hamburg 404 pp. Englisch. Seller Inventory # 9783838134796
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Geometric, Feature- and Graph-based Analysis of Protein Structures : Novel Methods and Computational Analysis
Published by
Südwestdeutscher Verlag Für Hochschulschriften AG Co. KG, 2013
ISBN 10: 3838134796
ISBN 13: 9783838134796
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The structural comparison of whole proteins or protein binding sites is usually performed by making use of graphs. Even though graphs exhibit a lot of interesting and useful properties, the usage of other representations can come along with several benefits. In this book the representation of a protein binding site is tackled. Three representations are considered namely the geometric, the feature-based and the graph-based representation. For all three types, some completely new algorithms are developed and presented. Moreover, existing methods are adapted to the application of protein binding sites' comparison. In addition, algorithms for the construction of multiple structural alignments are presented as a structural counterpart to multiple sequence alignment. By considering four different types of experiments, namely classification, similarity retrieval, clustering and construction of structural alignments, strengths and weaknesses of the proposed methods are detected and discussed. In addition a hybrid approach is presented which combines the benefits of a feature-based and a geometric method leading to a significant speed-up while still holding very good results. Seller Inventory # 9783838134796
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