Therapeutic efficacy of Praziquantel against Schistosoma mansoni: A study in Fincha River Valley, Ethiopia

 
9783845472959: Therapeutic efficacy of Praziquantel against Schistosoma mansoni: A study in Fincha River Valley, Ethiopia

Abstract: Schistosomiasis remains one of the most prevalent parasitic diseases in the sub-Saharan Africa including Ethiopia where Schistosoma mansoni and Schistosoma hematobium are widespread. praziquantel has been the most effective drug and used as mass chemotherapy. However, recently low cure rate recorded in different parts of the word. As it is the only drug used for schistosomiasis, there is a need to periodically evaluate the efficacy in different geographic settings. So this study evaluateed efficacy of Praziquantel against S.mansoni. Cross-sectional study was conducted in Fincha Valley followed by non randomized trial. Positive students treated with praziquantel 40mg/kg. Cure and reduction rate evaluated 4 weeks after treatment through fecal egg count by two Kato - Katz on two consecutive days. Data was analyzed and parasitological cure rate and egg reduction rate was 80.9% & 99.5% respectively. There was a significant association between cure rate and pre-treatment infection intensity (P > 0.05), but not between cure rate and age groups (P < 0.05). Praziquantel in a single dose remain efficacious despite prolonged use of the drug. However, further studies are needed.

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The author was born on December 20,1984 at Figa kobera Town in Western Wollega zone of oromia Regional state, Ethiopia. He obtained his BEd degree in Biology on July 17, 2006 and MSc in Medical Parasitology on July 19, 2010 at Jimma University and currently working in Haramaya University as lecturer and researcher since 2006.

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Book Description Book Condition: New. Publisher/Verlag: LAP Lambert Academic Publishing | A study in Fincha River Valley, Ethiopia | Abstract: Schistosomiasis remains one of the most prevalent parasitic diseases in the sub-Saharan Africa including Ethiopia where Schistosoma mansoni and Schistosoma hematobium are widespread. praziquantel has been the most effective drug and used as mass chemotherapy. However, recently low cure rate recorded in different parts of the word. As it is the only drug used for schistosomiasis, there is a need to periodically evaluate the efficacy in different geographic settings. So this study evaluateed efficacy of Praziquantel against S.mansoni. Cross-sectional study was conducted in Fincha Valley followed by non randomized trial. Positive students treated with praziquantel 40mg/kg. Cure and reduction rate evaluated 4 weeks after treatment through fecal egg count by two Kato - Katz on two consecutive days. Data was analyzed and parasitological cure rate and egg reduction rate was 80.9% & 99.5% respectively. There was a significant association between cure rate and pre-treatment infection intensity (P 0.05), but not between cure rate and age groups (P | Format: Paperback | Language/Sprache: english | 68 pp. Bookseller Inventory # K9783845472959

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Book Description LAP Lambert Acad. Publ. Sep 2011, 2011. Taschenbuch. Book Condition: Neu. Neuware - Abstract: Schistosomiasis remains one of the most prevalent parasitic diseases in the sub-Saharan Africa including Ethiopia where Schistosoma mansoni and Schistosoma hematobium are widespread. praziquantel has been the most effective drug and used as mass chemotherapy. However, recently low cure rate recorded in different parts of the word. As it is the only drug used for schistosomiasis, there is a need to periodically evaluate the efficacy in different geographic settings. So this study evaluateed efficacy of Praziquantel against S.mansoni. Cross-sectional study was conducted in Fincha Valley followed by non randomized trial. Positive students treated with praziquantel 40mg/kg. Cure and reduction rate evaluated 4 weeks after treatment through fecal egg count by two Kato - Katz on two consecutive days. Data was analyzed and parasitological cure rate and egg reduction rate was 80.9% & 99.5% respectively. There was a significant association between cure rate and pre-treatment infection intensity (P 0.05), but not between cure rate and age groups (P 68 pp. Englisch. Bookseller Inventory # 9783845472959

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Book Description LAP Lambert Acad. Publ. Sep 2011, 2011. Taschenbuch. Book Condition: Neu. Neuware - Abstract: Schistosomiasis remains one of the most prevalent parasitic diseases in the sub-Saharan Africa including Ethiopia where Schistosoma mansoni and Schistosoma hematobium are widespread. praziquantel has been the most effective drug and used as mass chemotherapy. However, recently low cure rate recorded in different parts of the word. As it is the only drug used for schistosomiasis, there is a need to periodically evaluate the efficacy in different geographic settings. So this study evaluateed efficacy of Praziquantel against S.mansoni. Cross-sectional study was conducted in Fincha Valley followed by non randomized trial. Positive students treated with praziquantel 40mg/kg. Cure and reduction rate evaluated 4 weeks after treatment through fecal egg count by two Kato - Katz on two consecutive days. Data was analyzed and parasitological cure rate and egg reduction rate was 80.9% & 99.5% respectively. There was a significant association between cure rate and pre-treatment infection intensity (P 0.05), but not between cure rate and age groups (P 68 pp. Englisch. Bookseller Inventory # 9783845472959

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Book Description LAP Lambert Academic Publishing, Germany, 2011. Paperback. Book Condition: New. Language: English . Brand New Book. Abstract: Schistosomiasis remains one of the most prevalent parasitic diseases in the sub-Saharan Africa including Ethiopia where Schistosoma mansoni and Schistosoma hematobium are widespread. praziquantel has been the most effective drug and used as mass chemotherapy. However, recently low cure rate recorded in different parts of the word. As it is the only drug used for schistosomiasis, there is a need to periodically evaluate the efficacy in different geographic settings. So this study evaluateed efficacy of Praziquantel against S.mansoni. Cross-sectional study was conducted in Fincha Valley followed by non randomized trial. Positive students treated with praziquantel 40mg/kg. Cure and reduction rate evaluated 4 weeks after treatment through fecal egg count by two Kato - Katz on two consecutive days. Data was analyzed and parasitological cure rate and egg reduction rate was 80.9 99.5 respectively. There was a significant association between cure rate and pre-treatment infection intensity (P > 0.05), but not between cure rate and age groups (P. Bookseller Inventory # KNV9783845472959

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Book Description LAP Lambert Academic Publishing. Paperback. Book Condition: New. Paperback. 68 pages. Dimensions: 8.7in. x 5.9in. x 0.2in.Abstract: Schistosomiasis remains one of the most prevalent parasitic diseases in the sub-Saharan Africa including Ethiopia where Schistosoma mansoni and Schistosoma hematobium are widespread. praziquantel has been the most effective drug and used as mass chemotherapy. However, recently low cure rate recorded in different parts of the word. As it is the only drug used for schistosomiasis, there is a need to periodically evaluate the efficacy in different geographic settings. So this study evaluateed efficacy of Praziquantel against S. mansoni. Cross-sectional study was conducted in Fincha Valley followed by non randomized trial. Positive students treated with praziquantel 40mgkg. Cure and reduction rate evaluated 4 weeks after treatment through fecal egg count by two Kato - Katz on two consecutive days. Data was analyzed and parasitological cure rate and egg reduction rate was 80. 9 and 99. 5 respectively. There was a significant association between cure rate and pre-treatment infection intensity (P 0. 05), but not between cure rate and age groups (P 0. 05). Praziquantel in a single dose remain efficacious despite prolonged use of the drug. However, further studies are needed. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Paperback. Bookseller Inventory # 9783845472959

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