C. elegans and Innate Immunity: A proteomic approach

 
9783847300465: C. elegans and Innate Immunity: A proteomic approach

The striking similarities between the innate defenses of vertebrates and invertebrates as well as the amenability of Caenorhabditis elegans for genetic analysis have made this free-living ground nematode a popular model system in the study of bacterial pathogenesis. Although genetic studies have brought new insights, showing the inducibility and pathogen-specificity of the immune response, there is still much to be discovered about the exact mechanisms underlying resistance to infection. In this study a different angle was adopted to study host–pathogen interactions in C. elegans. Given the dynamic nature of an immune response, the proteome of C. elegans was investigated at four different time-points (24, 48, 72, 96 h) after infection with S. typhi, S. typhi Ty21a, C. sakazakii and E. coli OP50 using SDS PAGE as a preliminary step to detect variation in the whole protein content.

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P.Srinivasan, M.Sc., PGADMD. He has attended 15 conferences at national and international level and have published 2 papers.He is currently doing research in Proteomics at Bundelkhand University,UP,India.M.Rajalakshmi, M.Sc.,PGADMD.,(PhD).,She has attended more than 10 conferences and is doing PUFA research at Bharathiyar University,TN,India.

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Book Description LAP Lambert Academic Publishing, United States, 2012. Paperback. Book Condition: New. 220 x 150 mm. Language: English . Brand New Book ***** Print on Demand *****.The striking similarities between the innate defenses of vertebrates and invertebrates as well as the amenability of Caenorhabditis elegans for genetic analysis have made this free-living ground nematode a popular model system in the study of bacterial pathogenesis. Although genetic studies have brought new insights, showing the inducibility and pathogen-specificity of the immune response, there is still much to be discovered about the exact mechanisms underlying resistance to infection. In this study a different angle was adopted to study host-pathogen interactions in C. elegans. Given the dynamic nature of an immune response, the proteome of C. elegans was investigated at four different time-points (24, 48, 72, 96 h) after infection with S. typhi, S. typhi Ty21a, C. sakazakii and E. coli OP50 using SDS PAGE as a preliminary step to detect variation in the whole protein content. Bookseller Inventory # AAV9783847300465

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Book Description LAP LAMBERT Academic Publishing. Paperback. Book Condition: New. Paperback. 100 pages. Dimensions: 8.7in. x 5.9in. x 0.2in.The striking similarities between the innate defenses of vertebrates and invertebrates as well as the amenability of Caenorhabditis elegans for genetic analysis have made this free-living ground nematode a popular model system in the study of bacterial pathogenesis. Although genetic studies have brought new insights, showing the inducibility and pathogen-specificity of the immune response, there is still much to be discovered about the exact mechanisms underlying resistance to infection. In this study a different angle was adopted to study hostpathogen interactions in C. elegans. Given the dynamic nature of an immune response, the proteome of C. elegans was investigated at four different time-points (24, 48, 72, 96 h) after infection with S. typhi, S. typhi Ty21a, C. sakazakii and E. coli OP50 using SDS PAGE as a preliminary step to detect variation in the whole protein content. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Paperback. Bookseller Inventory # 9783847300465

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