Interaction of Moxifloxacin: Drug Interaction, Method development by HPLC, Complexation, Organic synthesis, Antimicrobial and Enzymatic Activities

 
9783847333524: Interaction of Moxifloxacin: Drug Interaction, Method development by HPLC, Complexation, Organic synthesis, Antimicrobial and Enzymatic Activities

Moxifloxacin is a fourth generation fluoroquinolone has potent activity against Gram-positive bacteria, especially against pneumococcus and anaerobes, and still retain excellent activity against aerobic Gram-negative pathogens. I developed different methods for simultaneous determination of quinolones with different interacting drugs and performed drug-drug and drug-metals interactions by using these methods. We have synthesized derivatives and metal complexes of quinolones and characterized by physicochemical and spectroscopic methods (FT-IR, 1HNMR and mass spectrometry). The in-vitro antibacterial and antifungal activities of resulting complexes and derivatives were also performed and compared with the parent drug. Enzymatic activities of all synthesized compounds were carried out against different enzymes including urease, carbonic anhydrase, and α-chymotrypsin.

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About the Author:

Dr Mahwish Akhtar is working as Assistant professor in Dow University of Health Sciences. She has done B-Pharm from University of Karachi. Recently in the year 2011 she has got PhD degree in drug-drug interaction studies of moxifloxacin form University of Karachi. She has published several research papers in different International Journals.

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Book Description Book Condition: New. Publisher/Verlag: LAP Lambert Academic Publishing | Drug Interaction, Method development by HPLC, Complexation, Organic synthesis, Antimicrobial and Enzymatic Activities | Moxifloxacin is a fourth generation fluoroquinolone has potent activity against Gram-positive bacteria, especially against pneumococcus and anaerobes, and still retain excellent activity against aerobic Gram-negative pathogens. I developed different methods for simultaneous determination of quinolones with different interacting drugs and performed drug-drug and drug-metals interactions by using these methods. We have synthesized derivatives and metal complexes of quinolones and characterized by physicochemical and spectroscopic methods (FT-IR, 1HNMR and mass spectrometry). The in-vitro antibacterial and antifungal activities of resulting complexes and derivatives were also performed and compared with the parent drug. Enzymatic activities of all synthesized compounds were carried out against different enzymes including urease, carbonic anhydrase, and -chymotrypsin. | Format: Paperback | Language/Sprache: english | 388 pp. Bookseller Inventory # K9783847333524

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Book Description LAP Lambert Academic Publishing Mrz 2012, 2012. Taschenbuch. Book Condition: Neu. Neuware - Moxifloxacin is a fourth generation fluoroquinolone has potent activity against Gram-positive bacteria, especially against pneumococcus and anaerobes, and still retain excellent activity against aerobic Gram-negative pathogens. I developed different methods for simultaneous determination of quinolones with different interacting drugs and performed drug-drug and drug-metals interactions by using these methods. We have synthesized derivatives and metal complexes of quinolones and characterized by physicochemical and spectroscopic methods (FT-IR, 1HNMR and mass spectrometry). The in-vitro antibacterial and antifungal activities of resulting complexes and derivatives were also performed and compared with the parent drug. Enzymatic activities of all synthesized compounds were carried out against different enzymes including urease, carbonic anhydrase, and -chymotrypsin. 388 pp. Englisch. Bookseller Inventory # 9783847333524

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Book Description LAP Lambert Academic Publishing Mrz 2012, 2012. Taschenbuch. Book Condition: Neu. Neuware - Moxifloxacin is a fourth generation fluoroquinolone has potent activity against Gram-positive bacteria, especially against pneumococcus and anaerobes, and still retain excellent activity against aerobic Gram-negative pathogens. I developed different methods for simultaneous determination of quinolones with different interacting drugs and performed drug-drug and drug-metals interactions by using these methods. We have synthesized derivatives and metal complexes of quinolones and characterized by physicochemical and spectroscopic methods (FT-IR, 1HNMR and mass spectrometry). The in-vitro antibacterial and antifungal activities of resulting complexes and derivatives were also performed and compared with the parent drug. Enzymatic activities of all synthesized compounds were carried out against different enzymes including urease, carbonic anhydrase, and -chymotrypsin. 388 pp. Englisch. Bookseller Inventory # 9783847333524

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Book Description LAP Lambert Academic Publishing Mrz 2012, 2012. Taschenbuch. Book Condition: Neu. This item is printed on demand - Print on Demand Neuware - Moxifloxacin is a fourth generation fluoroquinolone has potent activity against Gram-positive bacteria, especially against pneumococcus and anaerobes, and still retain excellent activity against aerobic Gram-negative pathogens. I developed different methods for simultaneous determination of quinolones with different interacting drugs and performed drug-drug and drug-metals interactions by using these methods. We have synthesized derivatives and metal complexes of quinolones and characterized by physicochemical and spectroscopic methods (FT-IR, 1HNMR and mass spectrometry). The in-vitro antibacterial and antifungal activities of resulting complexes and derivatives were also performed and compared with the parent drug. Enzymatic activities of all synthesized compounds were carried out against different enzymes including urease, carbonic anhydrase, and -chymotrypsin. 388 pp. Englisch. Bookseller Inventory # 9783847333524

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Book Description LAP Lambert Academic Publishing, Germany, 2012. Paperback. Book Condition: New. Aufl.. Language: English . Brand New Book. Moxifloxacin is a fourth generation fluoroquinolone has potent activity against Gram-positive bacteria, especially against pneumococcus and anaerobes, and still retain excellent activity against aerobic Gram-negative pathogens. I developed different methods for simultaneous determination of quinolones with different interacting drugs and performed drug-drug and drug-metals interactions by using these methods. We have synthesized derivatives and metal complexes of quinolones and characterized by physicochemical and spectroscopic methods (FT-IR, 1HNMR and mass spectrometry). The in-vitro antibacterial and antifungal activities of resulting complexes and derivatives were also performed and compared with the parent drug. Enzymatic activities of all synthesized compounds were carried out against different enzymes including urease, carbonic anhydrase, and ?-chymotrypsin. Bookseller Inventory # KNV9783847333524

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Book Description LAP Lambert Academic Publishing. Paperback. Book Condition: New. 388 pages. Dimensions: 8.7in. x 5.9in. x 0.9in.Moxifloxacin is a fourth generation fluoroquinolone has potent activity against Gram-positive bacteria, especially against pneumococcus and anaerobes, and still retain excellent activity against aerobic Gram-negative pathogens. I developed different methods for simultaneous determination of quinolones with different interacting drugs and performed drug-drug and drug-metals interactions by using these methods. We have synthesized derivatives and metal complexes of quinolones and characterized by physicochemical and spectroscopic methods (FT-IR, 1HNMR and mass spectrometry). The in-vitro antibacterial and antifungal activities of resulting complexes and derivatives were also performed and compared with the parent drug. Enzymatic activities of all synthesized compounds were carried out against different enzymes including urease, carbonic anhydrase, and -chymotrypsin. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Paperback. Bookseller Inventory # 9783847333524

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