The Base Excision Repair Pathway: Molecular Mechanisms and Role in Disease Development and Therapeutic Design

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9789814719728: The Base Excision Repair Pathway: Molecular Mechanisms and Role in Disease Development and Therapeutic Design
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This book will serve as the preeminent text book on the topic of "base excision repair", a key DNA repair pathway that protects cells from most spontaneous forms of DNA damage, including oxidative lesions that arise both in the nuclear and mitochondrial genomes. The book, which includes contributions from many of the world leaders in the field, provides a detailed description of the molecular mechanisms of base excision repair, as well as its emerging relationship to epigenetic regulation, the aging process and human disease, such as cancer susceptibility, immunological defects and neurological disorders. The book will also cover the state-of-the-art technologies being developed to assess base excision repair capacity among individuals in the population, in addition to the strategies being employed to target base excision repair as part of therapeutic paradigms to eradicate disease, namely cancer.

This book represents one of the most extensive efforts to date to cover the topic of "base excision repair". It includes chapters by many of the most established investigators in the field, from all over the world.

Readership: Researchers, academics, scientists and clinicians, particularly for radiological and medical oncologists, epidemiologists, cancer prevention specialists, and graduate students in cancer biology, who are interested in DNA repair mechanisms and related susceptibility to cancer.

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David M Wilson
Published by World Scientific Publishing Co Pte Ltd, Singapore (2017)
ISBN 10: 9814719722 ISBN 13: 9789814719728
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Book Description World Scientific Publishing Co Pte Ltd, Singapore, 2017. Hardback. Condition: New. Language: English . This book usually ship within 10-15 business days and we will endeavor to dispatch orders quicker than this where possible. Brand New Book. This book will serve as the preeminent text book on the topic of base excision repair , a key DNA repair pathway that protects cells from most spontaneous forms of DNA damage, including oxidative lesions that arise both in the nuclear and mitochondrial genomes. The book, which includes contributions from many of the world leaders in the field, provides a detailed description of the molecular mechanisms of base excision repair, as well as its emerging relationship to epigenetic regulation, the aging process and human disease, such as cancer susceptibility, immunological defects and neurological disorders. The book will also cover the state-of-the-art technologies being developed to assess base excision repair capacity among individuals in the population, in addition to the strategies being employed to target base excision repair as part of therapeutic paradigms to eradicate disease, namely cancer.This book represents one of the most extensive efforts to date to cover the topic of base excision repair . It includes chapters by many of the most established investigators in the field, from all over the world. Seller Inventory # BTE9789814719728

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David M Wilson
Published by World Scientific Publishing Co Pte Ltd, Singapore (2017)
ISBN 10: 9814719722 ISBN 13: 9789814719728
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Book Description World Scientific Publishing Co Pte Ltd, Singapore, 2017. Hardback. Condition: New. Language: English . Brand New Book. This book will serve as the preeminent text book on the topic of base excision repair , a key DNA repair pathway that protects cells from most spontaneous forms of DNA damage, including oxidative lesions that arise both in the nuclear and mitochondrial genomes. The book, which includes contributions from many of the world leaders in the field, provides a detailed description of the molecular mechanisms of base excision repair, as well as its emerging relationship to epigenetic regulation, the aging process and human disease, such as cancer susceptibility, immunological defects and neurological disorders. The book will also cover the state-of-the-art technologies being developed to assess base excision repair capacity among individuals in the population, in addition to the strategies being employed to target base excision repair as part of therapeutic paradigms to eradicate disease, namely cancer.This book represents one of the most extensive efforts to date to cover the topic of base excision repair . It includes chapters by many of the most established investigators in the field, from all over the world. Seller Inventory # AAS9789814719728

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David M. Wilson
Published by World Scientific Publishing Co Pte Ltd 2017-02-09 (2017)
ISBN 10: 9814719722 ISBN 13: 9789814719728
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Book Description World Scientific Publishing Co Pte Ltd 2017-02-09, 2017. Condition: New. Brand new book, sourced directly from publisher. Dispatch time is 24-48 hours from our warehouse. Book will be sent in robust, secure packaging to ensure it reaches you securely. Seller Inventory # NU-MAR-00031511

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David M Wilson
Published by World Scientific Publishing Co Pte Ltd, Singapore (2017)
ISBN 10: 9814719722 ISBN 13: 9789814719728
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Book Description World Scientific Publishing Co Pte Ltd, Singapore, 2017. Hardback. Condition: New. Language: English . Brand New Book. This book will serve as the preeminent text book on the topic of base excision repair , a key DNA repair pathway that protects cells from most spontaneous forms of DNA damage, including oxidative lesions that arise both in the nuclear and mitochondrial genomes. The book, which includes contributions from many of the world leaders in the field, provides a detailed description of the molecular mechanisms of base excision repair, as well as its emerging relationship to epigenetic regulation, the aging process and human disease, such as cancer susceptibility, immunological defects and neurological disorders. The book will also cover the state-of-the-art technologies being developed to assess base excision repair capacity among individuals in the population, in addition to the strategies being employed to target base excision repair as part of therapeutic paradigms to eradicate disease, namely cancer.This book represents one of the most extensive efforts to date to cover the topic of base excision repair . It includes chapters by many of the most established investigators in the field, from all over the world. Seller Inventory # AAS9789814719728

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Book Description World Scientific Publishing Co, 2018. Hardcover. Condition: New. Never used! This item is printed on demand. Seller Inventory # 9814719722

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Book Description World Scientific Publishing Co. Condition: New. Hardcover. Worldwide shipping. FREE fast shipping inside USA (express 2-3 day delivery also available). Tracking service included. Ships from United States of America. Seller Inventory # 9814719722

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Wilson, David M.
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Book Description World Scientific Pub Co Inc, 2017. Hardcover. Condition: Brand New. 1st edition. 808 pages. 9.25x6.50x1.75 inches. In Stock. Seller Inventory # z-9814719722

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Book Description 2017. Hardcover. Condition: New. Hardcover. This book will serve as the preeminent text book on the topic of 'base excision repair', a key DNA repair pathway that protects cells from most spontaneous forms of DNA damage.Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability. 350 pages. 1.451. Seller Inventory # 9789814719728

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