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Applications of Baylis-Hillman Adducts

Raju Jannapu Reddy

ISBN 10: 3659201707 / ISBN 13: 9783659201707
Published by LAP Lambert Academic Publishing
New Condition: New Soft cover
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168 pages. Dimensions: 8.7in. x 5.9in. x 0.4in.The BaylisHillman (BH) reaction is a popular carboncarbon bond forming reaction. In the last decade, this reaction has received much attention and exponential growth due to its operational simplicity and enormous synthetic applications. The several reasons for the rapid growth of this reaction: (a) the starting materials are commerciallyreadily available; (b) atom-economic nature and mild reaction conditions; (c) usually involves a nucleophilic organocatalytic system without heavy-metal pollution; (d) the BaylisHillman adducts are multifunctional and are highly flexible. The main objectives of this work towards development of novel strategies for synthesis bioactive spiro and heterocyclic compounds from their BH adducts. The origin and growth of Baylis-Hillman reaction was briefly described in the first chapter. Recent and relevant synthetic applications of BH adducts were documented in chapter two. In third chapter, presented detailed studies of original and significant contributions of research results for synthesis biologically important spiro and heterocyclic compounds. Finally, the work is concluded giving an experimental details and references in the chapter four. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Bookseller Inventory # 9783659201707

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Bibliographic Details

Title: Applications of Baylis-Hillman Adducts

Publisher: LAP Lambert Academic Publishing

Binding: Paperback

Book Condition:New

Book Type: Paperback

About this title

Synopsis:

The Baylis–Hillman (BH) reaction is a popular carbon–carbon bond forming reaction. In the last decade, this reaction has received much attention and exponential growth due to its operational simplicity and enormous synthetic applications. The several reasons for the rapid growth of this reaction: (a) the starting materials are commercially/readily available; (b) atom-economic nature and mild reaction conditions; (c) usually involves a nucleophilic organocatalytic system without heavy-metal pollution; (d) the Baylis–Hillman adducts are multifunctional and are highly flexible. The main objectives of this work towards development of novel strategies for synthesis bioactive spiro and heterocyclic compounds from their BH adducts. The origin and growth of Baylis-Hillman reaction was briefly described in the first chapter. Recent and relevant synthetic applications of BH adducts were documented in chapter two. In third chapter, presented detailed studies of original and significant contributions of research results for synthesis biologically important spiro and heterocyclic compounds. Finally, the work is concluded giving an experimental details and references in the chapter four.

About the Author:

Dr Raju Jannapu Reddy obtained his PhD in 2008 from University of Hyderabad, India. He joined as a postdoctoral fellow in National Taiwan Normal University, Taiwan. He then moved to Kyoto Pharmaceutical University, Japan as a JSPS fellow. Recently, he awarded Marie Curie fellowship and he will move to University of Birmingham, UK from January 2013.

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