Applications Of Lc-Ms In Toxicology (Hb)

Polettini A.

ISBN 10: 0853696292 / ISBN 13: 9780853696292
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Synopsis: Analytical toxicologists are involved in the analysis of drugs and poisons in biological samples in different environments: therapeutic drug monitoring, drugs in sport, postmortem examinations, etc. Following the developments of LC-MS in the last decade and its establishment as the method of choice in the pharmaceutical industry (analytical R&D), the technique has gained favour in other scientific disciplines including analytical toxicology. This is notably due to the fact that purchase and operative costs of the equipment have gradually decreased over the same period. Many scientists in the field of analytical toxicology have already adopted LC-MS in their daily work, and this is illustrated by the increasing numbers of research papers published and presented at relevant conferences (The International Association of Forensic Toxicologists, Society of Forensic Toxicologists).

From the Back Cover: Following the developments of LC-MS in the last decade and its establishment as the method of choice in the pharmaceutical industry, the technique is increasingly being used in other scientific disciplines, including Clinical and Forensic Toxicology. Applications of LC-MS in Toxicology covers all essential theoretical aspects of LC-MS, comprising: technical details of the instrumentation and different operating modes, method development, optimisation and validation, quantification, and criteria for identification and confirmation. Further chapters cover in detail the application of LC-MS in areas such as: systematic toxicological analysis, drugs of abuse, therapeutic drug monitoring, doping in sport, pesticides, peptides and further forensic applications. This authoritative text is essential reading for all forensic and clinical toxicologists and will also be relevant to pharmaceutical analysts as well as analytical chemists.

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Title: Applications Of Lc-Ms In Toxicology (Hb)
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