The application of computational methods to DNA and protein science is a new and exciting development in biology. Bioinformatics: Sequence and Genome Analysis is a comprehensive introduction to this emerging field of study. The book has many unique and valuable features:

It is written for any biologist who wants to understand methods of sequence and structure analysis and how the necessary computer programs work

Sequence alignment, structure prediction, phylogenetic and gene prediction, database searching, and genome analysis are clearly explained and amply illustrated

Underlying algorithms and assumptions are clearly explained for the non-specialist

Examples are presented in simple numerical terms rather than complex formulas and notation

Theoretical underpinnings are linked to biological problems and their solutions

Extensive tables provide descriptions and Web sources for a broad range of publicly available software

Based on the author's extensive experience as a molecular geneticist and bioinformaticist at the University of Arizona, this is a uniquely educational book, ideal as a laboratory reference for investigators and also as teaching reference for graduate and undergraduate students studying this fast-changing discipline.

Review

Bioinformatics is an excellent text for the biologist who wants to learn more about the field, and is well worth exploring by the instructor looking to tackle his or her first bioinformatics course. Nature Genetics;...an excellent textbook for bioinformatics introductory courses for both life sciences and computer science students, and a good reference for current problems in the field and the tools and methods employed in their solution. --Briefings in Bioinformatics

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