CRISPR People: The Science and Ethics of Editing Humans

Greely, Henry T.

ISBN 10: 0262543885 / ISBN 13: 9780262543880

Published by The MIT Press, 2022

About this Item

Seller Inventory # 9780262543880

Bibliographic Details

• Title: CRISPR People: The Science and Ethics of Editing Humans
• Publisher: The MIT Press
• Publication Date: 2022
• Language: English
• ISBN 10: 0262543885
• ISBN 13: 9780262543880
• Binding: Paperback
• Condition: New

About this title

Synopsis

What does the birth of babies whose embryos had gone through genome editing mean--for science and for all of us?

In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos—as dramatic a development in genetics as the 1996 cloning of Dolly the sheep. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences. Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention.
 
The two babies, nonidentical twin girls, were the first “CRISPR'd” people ever born (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, is a powerful gene-editing method). Greely not only describes He's experiment and its public rollout (aided by a public relations adviser) but also considers, in a balanced and thoughtful way, the lessons to be drawn both from these CRISPR'd babies and, more broadly, from this kind of human DNA editing—“germline editing” that can be passed on from one generation to the next.
 
Greely doesn't mince words, describing He's experiment as grossly reckless, irresponsible, immoral, and illegal. Although he sees no inherent or unmanageable barriers to human germline editing, he also sees very few good uses for it—other, less risky, technologies can achieve the same benefits. We should consider the implications carefully before we proceed.

About the Author

Henry T. Greely is Professor of Law, Professor by Courtesy of Genetics, and Director of the Stanford Center for Law and the Biosciences at Stanford University, where he also chairs the Steering Committee of the Stanford University Center for Biomedical Ethics and directs the Stanford Program in Neuroscience and Society.