Stock Image

Cancer Stem Cells: Methods and Protocols

Yu, John S.

0 ratings by Goodreads
ISBN 10: 1617797537 / ISBN 13: 9781617797538
New Condition: New
From Pbshop (Wood Dale, IL, U.S.A.)

AbeBooks Seller Since August 20, 2015

Quantity Available: > 20

Buy New
Price: US$ 170.79 Convert Currency
Shipping: US$ 3.99 Within U.S.A. Destination, Rates & Speeds
Add to basket

30 Day Return Policy

About this Item

New Book.Shipped from US within 10 to 14 business days. Established seller since 2000. Bookseller Inventory # IB-9781617797538

Ask Seller a Question

Bibliographic Details

Title: Cancer Stem Cells: Methods and Protocols

Publication Date: 2012

Binding: PAP

Book Condition:New

About this title

Synopsis:

Cancer is a devastating disease that affects millions of people in the world. Our the- pies for tumors have mostly been based on classical chemotherapy and antiproliferative treatments. More recently, directed therapies against a causative oncogene have led to prominent reduction in tumor rates for some cancers. For instance, chronic myelogenous leukemia that is due to a BCR–ABL translocation can be targeted with Gleevec. Despite these advances in individual tumors, a number of patients are treated for their primary tumors and ultimately relapse. Relapsing tumors can be due to resistance to chemotherapy or to antioncogene drugs. Another hypothesis is that heterogeneity in the tumor leads to an inability of classical chemotherapy to completely eradicate all cells of the tumor. This concept of heterogeneity has led some investigators to propose a cancer stem cell model. As patients are treated with chemotherapy, most of the dividing cells are killed, but this leaves a small subset of cells that have the ability to remake the entire tumor. These are cancer stem cells. They possess the signals of self-renewal and yet can also differentiate. If one could understand more about the cells that remain after classical chemotherapy or the cells that can remake the tumor among the heterogeneous population, this information would have a huge impact on our treatment of cancer.

From the Back Cover:

Through the revolutionary concept of cancer stem cells, cancer research has been reinvigorated to study the role of these unique cells in cancer propagation and as targets of innovative therapies. In Cancer Stem Cells: Methods and Protocols, preeminent researchers have compiled cancer stem cell research techniques and protocols to promote healthy competition, discourse, and collaboration in this vital field.  The volume covers extensive topics such as identification and isolation of cancer stem cells, animal models of cancer stem cells, methylation profiling, the contribution of the niche in the regulation of cancer stem cells, immunologic targeting, and the use of normal stem cells as a treatment, among other subjects.  Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and expert notes on troubleshooting and avoiding known pitfalls.

Comprehensive and cutting-edge, Cancer Stem Cells: Methods and Protocols will aid scientists around the world in the furthering of our understanding of cancer initiation and propagation and, most importantly, in the development of novel targets for cancer therapy.

"About this title" may belong to another edition of this title.

Store Description

Visit Seller's Storefront

Terms of Sale:

Ordering - Please place your order via the AbeBooks website and allow 2 working days for dispatch from our US Warehouse. Delivery thereafter is 4 to 14 business days. Returns - We hope you will be delighted with everything you buy from us. However, if you do need to return an item to us, we kindly ask that goods are returned in their original condition within 14 days of receipt. In this instance the return cost must be borne by the buyer. In the event you receive an item which is not as advertis...

More Information
Shipping Terms:

Ships from our US Warehouse in approximately 2 working days. Delivery thereafter is 4 to 14 business days.

List this Seller's Books

Payment Methods
accepted by seller

Visa Mastercard American Express