Stock Image

Dendritic Cells in Human Atherosclerosis

Ilse Van Brussel

ISBN 10: 3659235407 / ISBN 13: 9783659235405
Published by LAP Lambert Academic Publishing
New Condition: New Soft cover
From BuySomeBooks (Las Vegas, NV, U.S.A.)

AbeBooks Seller Since May 21, 2012

Quantity Available: > 20

Buy New
List Price: US$ 101.00
Price: US$ 145.96 Convert Currency
Shipping: Free Within U.S.A. Destination, rates & speeds
Add to basket

30 Day Return Policy

About this Item

232 pages. Dimensions: 8.7in. x 5.9in. x 0.5in.Atherosclerosis is the main cause of death in the Western world. The importance of the immune system in the pathogenesis of atherosclerosis is now widely accepted. Here, we demonstrated that circulating dendritic cells (DC) the most professional antigen-presenting cells in the body - decline in coronary artery disease patients. This is - at least partly - due to impaired differentiation from bone marrow progenitors, but can also be explained by activation and subsequent migration to atherosclerotic plaques or lymph nodes. To be able to exert their function at inflammatory sites, DC need to be resistant to cell death induced by proatherogenic factors, such as oxLDL. Monocyte-derived DC seem to have an effective antioxidant defense system in comparison with monocytes, with high protein levels of peroxiredoxin 2 and glutathione peroxidase 3 among others. This enables them to survive in highly oxidative environments. Whether they enhance or delay the atherosclerotic process, or whether they are differently involved in the various stages of the disease, remains to be established. This book may be useful for anyone who is interested in the immunological aspects of atherosclerosis. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Bookseller Inventory # 9783659235405

Ask Seller a Question

Bibliographic Details

Title: Dendritic Cells in Human Atherosclerosis

Publisher: LAP Lambert Academic Publishing

Binding: Paperback

Book Condition:New

Book Type: Paperback

About this title

Synopsis:

Atherosclerosis is the main cause of death in the Western world. The importance of the immune system in the pathogenesis of atherosclerosis is now widely accepted. Here, we demonstrated that circulating dendritic cells (DC) – the most professional antigen-presenting cells in the body - decline in coronary artery disease patients. This is - at least partly - due to impaired differentiation from bone marrow progenitors, but can also be explained by activation and subsequent migration to atherosclerotic plaques or lymph nodes. To be able to exert their function at inflammatory sites, DC need to be resistant to cell death induced by proatherogenic factors, such as oxLDL. Monocyte-derived DC seem to have an effective antioxidant defense system in comparison with monocytes, with high protein levels of peroxiredoxin 2 and glutathione peroxidase 3 among others. This enables them to survive in highly oxidative environments. Whether they enhance or delay the atherosclerotic process, or whether they are differently involved in the various stages of the disease, remains to be established. This book may be useful for anyone who is interested in the immunological aspects of atherosclerosis.

About the Author:

Ilse Van Brussel, PhD. Graduated in 2007 as Master in Biomedical Sciences, then started a PhD at the lab of molecular and cellular cardiology (University of Antwerp) to explore the role of dendritic cells in atherosclerosis. Currently working as a postdoc at the lab of pharmacology, University of Antwerp.

"About this title" may belong to another edition of this title.

Store Description

BuySomeBooks is great place to get your books online. With over eight million titles available we're sure to have what you're looking for. Despite having a large selection of new books available for immediate shipment and excellent customer service, people still tell us they prefer us because of our prices.

Visit Seller's Storefront

Terms of Sale:

We guarantee the condition of every book as it's described on the Abebooks web
sites. If you're dissatisfied with your purchase (Incorrect Book/Not as
Described/Damaged) or if the order hasn't arrived, you're eligible for a refund
within 30 days of the estimated delivery date. If you've changed your mind about a book that you've ordered, please use the Ask bookseller a question link to contact us and we'll respond within 2 business days.

BuySomeBooks is operated by Drive-On-In, Inc., a Nevada co...

More Information
Shipping Terms:

Orders usually ship within 1-2 business days. Books are shipped from multiple locations so your order may arrive from Las Vegas,NV, Roseburg,OR, La Vergne,TN, Momence,IL, or Commerce,GA.

List this Seller's Books

Payment Methods
accepted by seller

Visa Mastercard American Express