Design,development and characterizationof orally disintegrating tablet

Abhishek Abhayrao Joshi (u. a.)

ISBN 10: 6204983431 / ISBN 13: 9786204983431

Published by LAP LAMBERT Academic Publishing, 2022

About this Item

Design,development and characterizationof orally disintegrating tablet | Abhishek Abhayrao Joshi (u. a.) | Taschenbuch | Englisch | 2022 | LAP LAMBERT Academic Publishing | EAN 9786204983431 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.

Seller Inventory # 122703355

Bibliographic Details

• Title: Design,development and characterizationof orally disintegrating tablet
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2022
• Language: English
• ISBN 10: 6204983431
• ISBN 13: 9786204983431
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 220W x 150H x 8D millimeters 220 millimeters width by 150 millimeters height by 8 millimeters depth
• Weight: 197 grams
• Seller catalogs:
  • Bücher

About this title

Synopsis

The present study was an attempt to select the best possible diluent - disintegrant combination to formulate Oral disintegrating tablets of Modafinil, which disintegrates in matter of seconds in the oral cavity, thereby reducing the time of onset of pharmacological action.Lycoat, Cross povidone and Sodium alginate, were used as disintegrants. In all the formulations, Magnesium stearate and talc were used as lubricant and glidant respectively.The results of the drug – excipient compatibility studies revealed that there was no chemical interaction between the pure drug and excipients.Direct compression method was employed to formulate the tablets, because of its cost effectiveness and due to reduced number of manufacturing steps.The precompression parameters like bulk density, tapped density, Carr’s index and angle of repose were determined. All the formulations showed acceptable flow properties.