Differential metabolic control analysis in cancer research: A Systems Biology perspective

Ettore Murabito

Published by LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3659229725 / ISBN 13: 9783659229725
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Synopsis: In the quest for anti-cancer drugs with high efficacy and low toxicity, cancer metabolism has increasingly been a focus of interest in clinical research. Enhanced glycolysis and robust production of lactate constitute characteristic traits that discriminate many cancerous cells from their normal counterparts. This, in principle, may provide researchers with a general handle on such a complex disease, regardless of the intrinsic genotypic heterogeneity of the single transformed cells. The work presented in this book consists of developing and applying analytical approaches, mainly drawn from the field of metabolic control analysis (MCA), to the study of cancer metabolism. The ultimate goal is to assess whether and to what extent the metabolic features of cancer cells may be exploited in the attempt to attack the malignancy more specifically than through traditional clinical approaches.

About the Author: At the time of publishing, Ettore Murabito works at the University of Manchester (UK) as research associate.

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Title: Differential metabolic control analysis in ...
Publisher: LAP LAMBERT Academic Publishing
Publication Date: 2012
Binding: Paperback
Book Condition: Good

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Book Description LAP Lambert Academic Publishing Sep 2012, 2012. Taschenbuch. Condition: Neu. Neuware - In the quest for anti-cancer drugs with high efficacy and low toxicity, cancer metabolism has increasingly been a focus of interest in clinical research. Enhanced glycolysis and robust production of lactate constitute characteristic traits that discriminate many cancerous cells from their normal counterparts. This, in principle, may provide researchers with a general handle on such a complex disease, regardless of the intrinsic genotypic heterogeneity of the single transformed cells. The work presented in this book consists of developing and applying analytical approaches, mainly drawn from the field of metabolic control analysis (MCA), to the study of cancer metabolism. The ultimate goal is to assess whether and to what extent the metabolic features of cancer cells may be exploited in the attempt to attack the malignancy more specifically than through traditional clinical approaches. 220 pp. Englisch. Seller Inventory # 9783659229725

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Book Description LAP Lambert Academic Publishing Sep 2012, 2012. Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Neuware - In the quest for anti-cancer drugs with high efficacy and low toxicity, cancer metabolism has increasingly been a focus of interest in clinical research. Enhanced glycolysis and robust production of lactate constitute characteristic traits that discriminate many cancerous cells from their normal counterparts. This, in principle, may provide researchers with a general handle on such a complex disease, regardless of the intrinsic genotypic heterogeneity of the single transformed cells. The work presented in this book consists of developing and applying analytical approaches, mainly drawn from the field of metabolic control analysis (MCA), to the study of cancer metabolism. The ultimate goal is to assess whether and to what extent the metabolic features of cancer cells may be exploited in the attempt to attack the malignancy more specifically than through traditional clinical approaches. 220 pp. Englisch. Seller Inventory # 9783659229725

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Book Description LAP Lambert Academic Publishing, Germany, 2012. Paperback. Condition: New. Aufl. Language: English. Brand new Book. In the quest for anti-cancer drugs with high efficacy and low toxicity, cancer metabolism has increasingly been a focus of interest in clinical research. Enhanced glycolysis and robust production of lactate constitute characteristic traits that discriminate many cancerous cells from their normal counterparts. This, in principle, may provide researchers with a general handle on such a complex disease, regardless of the intrinsic genotypic heterogeneity of the single transformed cells. The work presented in this book consists of developing and applying analytical approaches, mainly drawn from the field of metabolic control analysis (MCA), to the study of cancer metabolism. The ultimate goal is to assess whether and to what extent the metabolic features of cancer cells may be exploited in the attempt to attack the malignancy more specifically than through traditional clinical approaches. Seller Inventory # AAV9783659229725

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