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Epidemiology, Genotyping

Nivedita Gupta

ISBN 10: 3639175514 / ISBN 13: 9783639175516
Published by VDM Verlag
New Condition: New Soft cover
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About this Item

188 pages. Dimensions: 8.7in. x 5.9in. x 0.4in.This study is the first detailed analysis of Candida infections in burn patients in an Indian hospital. Burn patients are never subjected to fungal culture or given antifungals unless oral thrush develops. All attention goes to treat life threatening gram- negative bacterial septicemia. Often there is no significant bacterial culture positivity, still the patient deteriorates and dies. Study suggests that in such instances, patient might be suffering from fungal septicemia. This study is an attempt, expected to lead to better clinical management of burn patients. Interactions occurring between various bacteria and fungi in the burn wound are also analyzed, which may altogether alter the clinical prognosis of the patient. In agreement with earlier in vitro studies, it is observed that Pseudomonas significantly inhibits growth of Candida in vivo in the burn wound, either alone or in combination with other bacteria suggesting that Pseudomonas has an inhibitory effect on the growth of Candida. Results also suggest the involvement of some unknown genes and transcription factors in causing azole resistance in intrinsically resistant C. albicans clinical isolates. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Bookseller Inventory # 9783639175516

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Bibliographic Details

Title: Epidemiology, Genotyping

Publisher: VDM Verlag

Binding: Paperback

Book Condition:New

Book Type: Paperback

About this title

Synopsis:

This study is the first detailed analysis of Candida infections in burn patients in an Indian hospital. Burn patients are never subjected to fungal culture or given antifungals unless oral thrush develops. All attention goes to treat life threatening gram- negative bacterial septicemia. Often there is no significant bacterial culture positivity, still the patient deteriorates and dies. Study suggests that in such instances, patient might be suffering from fungal septicemia. This study is an attempt, expected to lead to better clinical management of burn patients. Interactions occurring between various bacteria and fungi in the burn wound are also analyzed, which may altogether alter the clinical prognosis of the patient. In agreement with earlier in vitro studies, it is observed that Pseudomonas significantly inhibits growth of Candida in vivo in the burn wound, either alone or in combination with other bacteria suggesting that Pseudomonas has an inhibitory effect on the growth of Candida. Results also suggest the involvement of some unknown genes and transcription factors in causing azole resistance in intrinsically resistant C. albicans clinical isolates.

About the Author:

Dr. Nivedita Gupta is a medical graduate. She studied fungal infections in burn patients in her PhD. as burns constitute a major cause of mortality in developing countries like India and fungal studies in burns are missing all over the world. She published two research papers in international journals out of this work.

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