Fast Oscillations in Cortical Circuits

Traub, Roger D. & Miles A. Whittington & John G. R. Jefferys

ISBN 10: 0262201186 ISBN 13: 9780262201186

Published by A Bradford Book, Cambridge, 1999

Language: English

Condition: Used - Near fine Hardcover

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Small remainder mark on one edge. A nice, crisp copy. ; Computational Neuroscience; 9.1 X 6.1 X 1.2 inches; 324 pages.

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Bibliographic Details

Title

Fast Oscillations in Cortical Circuits

Publisher

A Bradford Book, Cambridge

Publication Date

1999

Language

English

ISBN 10

0262201186

ISBN 13

9780262201186

Binding

Hardcover

Condition

Near Fine

Dust Jacket Condition

Near Fine

Weight

3 pounds

Seller catalogs

Neuroscience/Cognitive Science

About this title

Synopsis

The study of cortical oscillations is of great interest to those working in many areas of neuroscience. A fast coherent EEG rhythm called gamma or "40 Hz" has been implicated in cognition, as it may play a role in binding together features of objects. This rhythm may also be important for consciousness, as a number of drugs that induce general anesthesia disrupt the synchronization of the rhythm at clinically relevant concentrations. There is also suggestive evidence implicating dysfunction of gamma rhythms in Alzheimer's disease, and perhaps in other neuropsychiatric disorders.

In Fast Oscillations in Cortical Circuits, the authors use a combination of electrophysiological and computer modeling techniques to analyze how large networks of neurons can produce both epileptic seizures and functionally relevant synchronized oscillations. Specific topics covered include single hippocampal pyramid cells, hippocampal interneurons, synaptic interactions, gamma oscillations in brain slices as well as in vivo, the mechanisms of oscillation-synchronization (both local and long-range), the switch from gamma to beta frequencies and its implications for memory, and the significance of gamma oscillations for brain function.

About the Author

Miles A. Whittington is Lecturer in the Department of Physiology at Imperial College, London, UK.

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