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Gastroprotective and Antisecretory Activity of Selenomethionine

krishnamoorthy Machina

ISBN 10: 3844391835 / ISBN 13: 9783844391831
Published by LAP Lambert Academic Publishing
New Condition: New Soft cover
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Paperback. 128 pages. Dimensions: 8.7in. x 5.9in. x 0.3in.The present work deals with the antisecretory and gastroprotective effect of selenomethionine in swiss albino rat system by using 1. 4 hour Pylorus ligation model for antisecretory activity using the following pathophysiological and biochemical parameters in gastric juice and gastric mucosa a) Ulcer index measurement of the glandular portion of the stomach, b) Measurement of volume, pH, free and total acidity, peptic activity, DNA content of the gatsric juice and c) Total protein, carbohydrate estimation in gastric juice and gastric mucosa, 2. ethanol induced gastric ulcer model using a)Ulcer index measurement, b) Gastric wall mucous content estimation and c)Lipid peroxide level estimation, 3. stress induced ulcer model using a) Measurement of ulcer index, b)Estimation of gastric wall mucus content and 4. Aspirin induced gastric ulcer model of ulcer index measurement. Antiulcer and cytoprotective effect of Selenomethionine and reference drug Cemetidine in rats are studied in the above validated gastric ulcer models after a desired period of drug administration. This work works at the development of a novel gastroprotective molecule. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Bookseller Inventory # 9783844391831

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Bibliographic Details

Title: Gastroprotective and Antisecretory Activity ...

Publisher: LAP Lambert Academic Publishing

Binding: Paperback

Book Condition:New

Book Type: Paperback

About this title

Synopsis:

The present work deals with the antisecretory and gastroprotective effect of selenomethionine in swiss albino rat system by using 1. 4 hour Pylorus ligation model for antisecretory activity using the following pathophysiological and biochemical parameters in gastric juice and gastric mucosa a) Ulcer index measurement of the glandular portion of the stomach, b) Measurement of volume, pH, free and total acidity, peptic activity, DNA content of the gatsric juice and c) Total protein, carbohydrate estimation in gastric juice and gastric mucosa, 2. ethanol induced gastric ulcer model using a)Ulcer index measurement,b) Gastric wall mucous content estimation and c)Lipid peroxide level estimation, 3. stress induced ulcer model using a) Measurement of ulcer index, b)Estimation of gastric wall mucus content and 4. Aspirin induced gastric ulcer model of ulcer index measurement. Antiulcer and cytoprotective effect of Selenomethionine and reference drug Cemetidine in rats are studied in the above validated gastric ulcer models after a desired period of drug administration. This work works at the development of a novel gastroprotective molecule.

About the Author:

Dr.M.Krishnamoorthy obtained his post-graduation in Biosciences in 1974, from Mysore University. He did his doctoral studies in the area of Mammalian Psychophysiology. Currently he is working as a professor in the Department of Biosciences, Mangalore University, India.His area of research are Cancer Biology and cytogenetics.

Dr.M.Krishnamoorthy obtained his post-graduation in Biosciences in 1974, from Mysore University. He did his doctoral studies in the area of Mammalian Psychophysiology. Currently he is working as a professor in the Department of Biosciences, Mangalore University, India.His area of research are Cancer Biology and cytogenetics.

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