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Genetics: Analysis of Genes and Genomes, (Eighth Edition)

Daniel L. Hartl,Maryellen Ruvolo

ISBN 10: 9380853408 / ISBN 13: 9789380853406
Published by Jones & Bartlett India Private Limited/Viva Books, 2012
New Condition: New Soft cover
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Thoroughly revised and updated with the latest data from this ever-changing field, the eighth edition of Genetics: Analysis of Genes and Genomes provides a clear, balanced, and comprehensive introduction to genetics and genomics at the college level. Expanding upon the key elements that have made this text a success, Dr. Hartl has included updates throughout, as well as a new chapter dedicated to human genetic evolution. He continues to treat transmission genetics, molecular genetics, and evolutionary genetics as fully integrated subjects and provides students with an unprecedented understanding of the basic process of gene transmission, mutation, expression, and regulation. The beginning of each chapter includes a new section highlighting scientific competencies, while end-of-chapter Guide to Problem-Solving sections demonstrate the concepts needed to solve problems efficiently and understand the reasoning behind the correct answer. New and Key Features of the Eighth Edition: ? A new Chapter 19, Human Evolutionary Genetics. ? Learning Objectives & Scientific Competencies added to the beginning of each chapter. ? New problem sets in the accompanying ancillary material. ? Updated throughout with the latest data in this fast-paced field including new sections on Telomere Length Limits and Number of Cell Doublings; CNV with Reciprocal Risks of Autism and Schizophrenia; Translation Proofreading and Premature Termination; Stochastic Noise in Gene Expression; Stochastic Noise in lac Expression; and Long Noncoding RNA (IncRNA). Contents: Genes, Genomes and Genetic Analysis ? Learning Objectives & Science Competencies ? DNA: The Genetic Material ? Experimental Proof of the Genetic Function of DNA ? Genetic Role of DNA in Bacteriophage ? DNA Structure and Replication ? An Overview of DNA Replication ? Genes and Proteins ? Inborn Errors of Metabolism as a Cause of Hereditary Disease ? Genetic Analysis ? Mutant Genes and Defective Proteins ? Complementation Test for Mutations in the Same Gene ? Analysis of Complementation Data ? Other Applications of Genetic Analysis ? Gene Expression: The Central Dogma ? Transcription ? Translation ? The Genetic Code ? Mutation ? Genes and Environment ? The Molecular Unity of Life ? Prokaryotes and Eukaryotes ? The Origin of Life on Earth ? Genomes and Proteomes ? Chapter Summary ? Review the Basics ? Guide to Problem Solving ? Analysis and Applications ? Challenge Problems ? Connection: The Black Urine Disease ? Connection: One Gene, One Enzyme DNA Structure and Genetic Variation ? Learning Objectives & Science Competencies ? Genetic Differences Among Individuals ? DNA Markers as Landmarks in Chromosomes ? The Molecular Structure of DNA ? Polynucleotide Chains ? Base Pairing and Base Stacking ? Antiparallel Strands ? DNA Structure as Related to Function ? The Separation and Identification of Genomic DNA Fragments ? Restriction Enzymes and Site- Specific DNA Cleavage ? Gel Electrophoresis ? Nucleic Acid Hybridization ? The Southern Blot ? Selective Replication of Genomic DNA Fragments ? Constraints on DNA Replication: Primers and 5?-to-3? Strand Elongation ? The Polymerase Chain Reaction ? The Terminology of Genetic Analysis ? Types of DNA Markers Present in Genomic DNA ? Single-Nucleotide Polymorphisms (SNPs) ? Restriction Fragment Length Polymorphisms (RFLPs) ? Tandem Repeat Polymorphisms ? Copy-Number Variation (CNV) ? Applications of DNA Markers ? Genetic Markers, Genetic Mapping, and ?Disease Genes? ? Other Uses for DNA Markers ? Chapter Summary ? Review the Basics ? Guide to Problem Solving ? Analysis and Applications ? Challenge Problems ? Connection: The Double Helix ? Connection: Origin of the Human Genetic Linkage Map Transmission Genetics: The Principle of Segregation ? Learning Objectives & Science Competencies ? Morphological an Printed Pages: 822. Bookseller Inventory # 35927

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Title: Genetics: Analysis of Genes and Genomes, (...

Publisher: Jones & Bartlett India Private Limited/Viva Books

Publication Date: 2012

Binding: Softcover

Book Condition:New

Edition: 5th or later edition.

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