Immunobiology of Bacterial CpG-DNA (Current Topics in Microbiology and Immunology, Volume 247)

Wagner, H.

Published by Springer, 2000
ISBN 10: 3540664009 / ISBN 13: 9783540664000
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Synopsis: Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules and pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book is the first comprehensive review of the data emerging in this field.

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Title: Immunobiology of Bacterial CpG-DNA (Current ...
Publisher: Springer
Publication Date: 2000
Book Condition: Good

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