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Leave the Lights on

Alejandro Murad

ISBN 10: 3844393277 / ISBN 13: 9783844393279
Published by LAP LAMBERT Academic Publishing
New Condition: New Soft cover
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About this Item

Paperback. 160 pages. Dimensions: 8.7in. x 5.9in. x 0.4in.Most organisms, from cyanobacteria to humans are equipped with circadian clocks. These endogenous and self-sustained pacemakers allow organisms to adapt their physiology and behavior to daily environmental variations, and to anticipate them. The circadian clock is synchronized by environmental cues (i. e. light and temperature fluctuations). The fruit fly, Drosophila melanogaster, is a well established model for the study of circadian rhythms. Molecular mechanisms of the Drosophila circadian clock are conserved in mammals. This dissertation focuses on identifying the Drosophila pacemaker neurons that drive circadian rhythms in constant light (LL). The results presented here suggest that a subset of pacemaker neurons, the DN1s, is responsible for driving rhythms in constant light. This attractive finding reveals a novel role for the DN1s in driving behavioral rhythms under constant conditions and suggests a mechanism for seasonal adaptation in Drosophila. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Bookseller Inventory # 9783844393279

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Bibliographic Details

Title: Leave the Lights on

Publisher: LAP LAMBERT Academic Publishing

Binding: Paperback

Book Condition:New

Book Type: Paperback

About this title

Synopsis:

Most organisms, from cyanobacteria to humans are equipped with circadian clocks. These endogenous and self-sustained pacemakers allow organisms to adapt their physiology and behavior to daily environmental variations, and to anticipate them. The circadian clock is synchronized by environmental cues (i.e. light and temperature fluctuations). The fruit fly, Drosophila melanogaster, is a well established model for the study of circadian rhythms. Molecular mechanisms of the Drosophila circadian clock are conserved in mammals. This dissertation focuses on identifying the Drosophila pacemaker neurons that drive circadian rhythms in constant light (LL). The results presented here suggest that a subset of pacemaker neurons, the DN1s, is responsible for driving rhythms in constant light. This attractive finding reveals a novel role for the DN1s in driving behavioral rhythms under constant conditions and suggests a mechanism for seasonal adaptation in Drosophila.

About the Author:

Dr. Alejandro Murad was born in Buenos Aires, Argentina. After finishing his Masters Degree in Biotechnology, he moved to Massachusetts where he obtained a Ph.D. in Neurobiology from the University of Massachusetts Medical School. Currently his research focuses on drug development for neurodegenerative disorders.

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