The Long and Short Non-coding RNAs in Cancer Biology

Book 242 of 544: Advances in Experimental Medicine and Biology

Erwei Song

ISBN 10: 9811014965 ISBN 13: 9789811014963

Published by Springer Singapore, 2016

Language: English

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Bibliographic Details

Title

The Long and Short Non-coding RNAs in Cancer Biology

Publisher

Springer Singapore

Publication Date

2016

Language

English

ISBN 10

9811014965

ISBN 13

9789811014963

Binding

Buch

Condition

Neu

Dimensions

Weight

863 grams

Seller catalogs

B�cher

About this title

Synopsis

The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance), the role of ncRNAs in regulating cancer signaling circuitry programs (highlighting their involvement in c-myc, p53 and NFkB signaling), a systemic summary of clinical and preclinical studies that evaluate the potential of ncRNA signatures for cancer diagnosis and prognosis and strategies to delivery short ncRNAs as therapeutic molecules for cancer treatment. This book may serve as a comprehensive resource for researchers, graduate students and oncologists in ncRNA and cancer research and help drug development by identifying ncRNA targets.

About the Author

Dr. Erwei Song is a professor at SunYat-Sen Memorial Hospital, Guangzhou, China.

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