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Metabolome Analysis: An Introduction

Silas G. Villas-Boas

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ISBN 10: 0471743445 / ISBN 13: 9780471743446
Published by Wiley-Interscience, 2007
New Condition: New Hardcover
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Bibliographic Details

Title: Metabolome Analysis: An Introduction

Publisher: Wiley-Interscience

Publication Date: 2007

Binding: Hardcover

Book Condition:New

Edition: 1.

About this title

Synopsis:

Providing information on the main approaches for the analysis ofmetabolites, this textbook:

  • Covers basic methodologies in sample preparation and separationtechniques, as well as the most recent techniques of massspectrometry.
  • Differentiates between primary and secondary metabolites.
  • Includes four chapters discussing successful metabolome studiesof different organisms.
  • Highlights the analytical challenges of studyingmetabolites.
  • Illustrates applications of metabolome analysis through the useof case studies.

From the Back Cover:

A concise, interdisciplinary introduction to metabolome analysis

This practical reference focuses on the principles of metabolomeanalysis and treats metabolomics as a field of its own, rather thanas just an additional analytical tool in science. Part I guidesreaders through the primary steps in metabolite analysis, beginningwith an overview of the terminology and the basic concepts of cellmetabolism, and the dynamics of biochemical reactions andmetabolite turnover. It then discusses the most commonmethodologies for sample preparation, sample techniques, detectionand identification methods, analytical tools (including liquid andgas chromatography as well as mass spectrometry), and dataanalysis.

Part II illustrates the applicability of metabolomics anddiscusses specific peculiarities and requirements of metabolomicsin certain groups of organisms. It reviews successful cases ofmetabolome analysis with chapters on:

  • Yeast metabolomics
  • Specialized sampling devices for microbial metabolomics
  • Major achievements in plant metabolomics
  • Metabolomics in the classification of filamentous fungi
  • Metabolomics applied to humans and other mammals

This is the definitive, core reference on metabolome analysisfor research scientists in biochemistry and analytical chemistry,as well as academics, researchers, and technicians in the fields offunctional genomics and metabolic engineering. It is also apractical text for scientists working to discover metabolites fromnatural sources and for graduate students in a variety ofcourses.

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