Metal Ions in Biological Systems: Antibiotics and Their Complexes

Sigel, Helmut

Published by CRC Press, 1985
ISBN 10: 0824774256 / ISBN 13: 9780824774257
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Synopsis: Metal Ions in Biological Systems is devoted to increasing our understanding of the relationship between the chemistry of metals and life processes The volumes reflect the interdisciplinary nature of bioinorganic chemistry and coordinate the efforts of researchers in the fields of biochemistry inorganic chemistry coordination chemistry environmental chemistry biophysics pharmacy and medicine Volumes deal with such topics as the formation stability structure and reactivity of biological compounds of low and high molecular weight containing metal ions the metabolism and transport of metal ions and their complexes and new models of complicated natural structures and processes Volume 21 describes the underlying theories of nuclear magnetic resonance NMR promoting a wider use of NMR in studies of paramagnetic species In six concise chapters by leading international authorities Applications of Nuclear Magnetic Resonance to Paramagnetic Species outlines the most recent developments regarding the use of nuclear relaxation as a source for structural information examines studies of magnetically coupled metalloproteins and metal porphyrin induced dipolar shifts for conformational analysis and evaluates the potential of paramagnetic ions as agents for enhancing NMR image contrast With over 500 references that facilitate further research Applications of Nuclear Magnetic Resonance to Paramagnetic Species is an essential resource for scientists and students in such disciplines as biophysics bioinorganic inorganic and coordination chemistry biochemistry molecular biology and enzymology Book jacket

From the Back Cover: Metal Ions in Life Sciences links coordination chemistry and biochemistry in their widest sense and thus increases our understanding of the relationship between the chemistry of metals and life processes. The series reflects the interdisciplinary nature of Biological Inorganic Chemistry and coordinates the efforts of scientists in fields like biochemistry, inorganic and coordination chemistry, molecular and structural biology, enzymology, environmental chemistry, physiology, toxicology, biophysics, pharmacy, and medicine. Consequently, the volumes are an essential source for researchers active in these and related fields as well as teachers preparing courses, e.g., in Bioinorganic Chemistry.

Volume 1, offers in 15 stimulating chapters an authoritative view of the fascinating research on Neurodegenerative Diseases and Metal Ions. Written by 41 internationally recognized experts, ithighlights, supported by 130 illustrations, the recent progress made in understanding the role metal ions play in diseases like transmissible spongiform encephalo­pathies (Creutzfeldt-Jakob and related diseases), Alzheimer's, Parkinson's, Huntington's, Wilson's and Menkes' diseases, as well as in familial amyotrophic lateral sclerosis and others. The interplay between metal ions, catecholamines and the formation of reactive oxygen species resulting in oxidative stress is considered, as is the metalloneurochemistry of zinc and the neurotoxicity of aluminum, cadmium, lead, and mercury. The need for novel drugs which manipulate metal-centered neuropathology is emphasized. With more than 2000 references this book is a vital resource for scientists and advanced students.

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Bibliographic Details

Title: Metal Ions in Biological Systems: ...
Publisher: CRC Press
Publication Date: 1985
Binding: HRD
Book Condition: New

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Sigel, Helmut
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Book Description CRC Press. Condition: Good. Volume 19. Ex-library, so some stamps and wear, but in good overall condition. Seller Inventory # Z1-M-016-00816

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Book Description Marcel Dekker, 1985. Hardcover. Condition: Very Good. Light wear and soiling to covers, otherwise text clean and solid; no dust jacket; Antibiotics and Their Complexes; Vol. 19; 1.02 x 9.13 x 6.3 Inches; 464 pages. Seller Inventory # 159748

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