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Modern Analytical Techniques to Study Novel Anticancer Compounds

Amal Hamad

ISBN 10: 3847313657 / ISBN 13: 9783847313656
Published by LAP Lambert Academic Publishing
New Condition: New Paperback
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Paperback. 176 pages. Dimensions: 8.7in. x 5.9in. x 0.4in.Analytical Chemistry is at the core of drug discovery and this work focuses on the use of modern techniques to study interactions of novel metallo anticancer compounds with biological targets which is crucial to better develop them. The studied compounds include supramolecular iron cylinders which should offer a new mode of binding to DNA, and steroid platinum and rhenium compounds aiming at better targeting cancer cells. In order to study these compounds interactions with DNA and proteins, a myriad of modern techniques were used including linear and circular dichroism, surface plasmon resonance, IR LASER imaging, gel electrophoresis, ESI-MS, fluorescence and UV-Vis spectroscopy. This work is a humble contribution in the very complicated quest of developing more selective anticancer compounds. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Bookseller Inventory # 9783847313656

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Bibliographic Details

Title: Modern Analytical Techniques to Study Novel ...

Publisher: LAP Lambert Academic Publishing

Binding: Paperback

Book Condition:New

Book Type: Paperback

About this title

Synopsis:

Analytical Chemistry is at the core of drug discovery and this work focuses on the use of modern techniques to study interactions of novel metallo anticancer compounds with biological targets which is crucial to better develop them. The studied compounds include supramolecular iron cylinders which should offer a new mode of binding to DNA, and steroid platinum and rhenium compounds aiming at better targeting cancer cells. In order to study these compounds interactions with DNA and proteins, a myriad of modern techniques were used including linear and circular dichroism, surface plasmon resonance, IR LASER imaging, gel electrophoresis, ESI-MS, fluorescence and UV-Vis spectroscopy. This work is a humble contribution in the very complicated quest of developing more selective anticancer compounds.

About the Author:

Dr. Amal E. Hamad is a lecturer of Analytical Chemistry, Faculty of Pharmacy, Minia University, Egypt and a previous member of Prof. Michael J. Hannon group, Chair of Chemical Biology, University of Birmingham, UK.

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