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Mystery of Bronze Diabetes

Mohamed Ahmed

ISBN 10: 363920560X / ISBN 13: 9783639205602
Published by VDM Verlag
New Condition: New Soft cover
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About this Item

152 pages. Dimensions: 8.7in. x 5.9in. x 0.3in.Hereditary Hemochromatosis (HH) is called Bronze Diabetes as the skin of the sufferers of this disease turns bronze due to iron overload that usually accompanies this disease. Healthy people usually store up to 4 grams of iron in their body while patients with hemochromatosis exceed this limit. This extra iron distributes all over the body staring with liver and ending with pancreas, heart, pituitary glands and skin. The most common clinical symptoms of the disease include, deep fatigue, joint pain, erectile dysfunction, diabetes, cardiomegaly, Jaundice, cirrhotic liver and cancer. Bronze diabetes is diagnosed phenotypically by the detection of ferritin, total binding and transferrin saturation in serum samples. Bronze diabetes is treated by phelobotomy which means draining the blood from the body. Phelobotomies are carried out on weeky basis until the serum levels of ferritin are down as well as the transferrin saturation. Once this goal is achieved, this process is repeated every few months. In this study, we are attempting to highlight the role of transferrin oxidative modification and carbonyl atress in pathophysiology of HH. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Bookseller Inventory # 9783639205602

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Bibliographic Details

Title: Mystery of Bronze Diabetes

Publisher: VDM Verlag

Binding: Paperback

Book Condition:New

Book Type: Paperback

About this title

Synopsis:

Hereditary Hemochromatosis (HH) is called Bronze Diabetes as the skin of the sufferers of this disease turns bronze due to iron overload that usually accompanies this disease. Healthy people usually store up to 4 grams of iron in their body while patients with hemochromatosis exceed this limit. This extra iron distributes all over the body staring with liver and ending with pancreas, heart, pituitary glands and skin. The most common clinical symptoms of the disease include, deep fatigue, joint pain, erectile dysfunction, diabetes, cardiomegaly, Jaundice, cirrhotic liver and cancer. Bronze diabetes is diagnosed phenotypically by the detection of ferritin, total binding and transferrin saturation in serum samples. Bronze diabetes is treated by phelobotomy which means draining the blood from the body. Phelobotomies are carried out on weeky basis until the serum levels of ferritin are down as well as the transferrin saturation. Once this goal is achieved, this process is repeated every few months. In this study, we are attempting to highlight the role of transferrin oxidative modification and carbonyl atress in pathophysiology of HH.

About the Author:

? Currently, PhD Candidate, Dept. of Medicine, University of Saskatchewan, Canada. ? MSc in pathology, Division of Clinical Biochemistry, College of Medicine, University of Saskatchewan, Canada; 2007 ? Bachelor of Medical Sciences, College of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada; 2002

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