NON-PROTEIN-CODING RNAS MEDIATE FINE-TUNED GENE EXPRESSION | VOLUME ONE: REGULATORY ROLES OF NATURAL ANTISENSE TRANSCRIPTS

Mohammad Ali Faghihi

ISBN 10: 3838323947 / ISBN 13: 9783838323947

Published by LAP LAMBERT Academic Publishing, 2010

About this Item

NON-PROTEIN-CODING RNAS MEDIATE FINE-TUNED GENE EXPRESSION | VOLUME ONE: REGULATORY ROLES OF NATURAL ANTISENSE TRANSCRIPTS | Mohammad Ali Faghihi | Taschenbuch | 128 S. | Englisch | 2010 | LAP LAMBERT Academic Publishing | EAN 9783838323947 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu.

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Bibliographic Details

• Title: NON-PROTEIN-CODING RNAS MEDIATE FINE-TUNED GENE EXPRESSION | VOLUME ONE: REGULATORY ROLES OF NATURAL ANTISENSE TRANSCRIPTS
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2010
• Language: English
• ISBN 10: 3838323947
• ISBN 13: 9783838323947
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 220W x 150H x 8D millimeters 220 millimeters width by 150 millimeters height by 8 millimeters depth
• Weight: 209 grams
• Seller catalogs:
  • Bücher

About this title

Synopsis

Natural antisense transcripts: The human genome sequencing projects revealed that the human genome consist of over 3 billion DNA base pairs, but only contain 20,000?25,000 genes that are encoding proteins. Recent studies have revealed that eukaryotic genomes are almost entirely transcribed, generating an enormous number of non-protein-coding RNAs. Several classes of functional non-protein-coding RNAs have been identified in recent years. One prominent and complex class of regulatory RNAs is natural antisense transcripts. Mammalian genomes encode numerous natural antisense transcripts, but the function of these transcripts is not well understood. Functional validation studies indicate that antisense transcripts are not a uniform regulatory RNA group, but instead belong to multiple categories with some common features. Recent evidence presented in this book indicates that antisense transcripts are frequently functional and use diverse transcriptional and post- transcriptional gene regulatory mechanisms to carry out a wide variety of biological roles.