Neurotrophic Factors and Their Receptors: The structural and functional studies of GDNF and MANF/CDNF family of neurotrophic factors

parkash, vimal

Published by LAP Lambert Academic Publishing, 2009
ISBN 10: 3838322460 / ISBN 13: 9783838322469
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Synopsis: Four GDNF ligands (GDNF, neurturin, artemin and persephin), and mesencephalic astrocyte-derived neurotrophic factor (MANF) and conserved dopamine neurotrophic factor (CDNF) protect midbrain dopaminergic neurons that degenerate in Parkinson's disease. Each GDNF ligand binds a specific coreceptor GDNF family receptor ? (GFR?), leading to the formation of a heterotetramer complex, which then interacts with receptor tyrosine kinase RET, the signalling receptor. The present work describes the structural and biochemical characterization of the GDNF-GFR?1 complex and the MANF and CDNF proteins.

About the Author: Vimal Parkash, Ph.D. in Biochemistry from University of Helsinki, Finland, Postdoctoral researcher at the university of Helsinki in Adrian Goldman's laboratory.

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Title: Neurotrophic Factors and Their Receptors: ...
Publisher: LAP Lambert Academic Publishing
Publication Date: 2009
Binding: Paperback
Book Condition: Used: Good

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Published by LAP Lambert Acad. Publ. Nov 2009 (2009)
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Book Description LAP Lambert Acad. Publ. Nov 2009, 2009. Taschenbuch. Book Condition: Neu. Neuware - Four GDNF ligands (GDNF, neurturin, artemin and persephin), and mesencephalic astrocyte-derived neurotrophic factor (MANF) and conserved dopamine neurotrophic factor (CDNF) protect midbrain dopaminergic neurons that degenerate in Parkinson's disease. Each GDNF ligand binds a specific coreceptor GDNF family receptor (GFR ), leading to the formation of a heterotetramer complex, which then interacts with receptor tyrosine kinase RET, the signalling receptor. The present work describes the structural and biochemical characterization of the GDNF-GFR 1 complex and the MANF and CDNF proteins. 92 pp. Englisch. Bookseller Inventory # 9783838322469

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Book Description LAP Lambert Acad. Publ. Nov 2009, 2009. Taschenbuch. Book Condition: Neu. Neuware - Four GDNF ligands (GDNF, neurturin, artemin and persephin), and mesencephalic astrocyte-derived neurotrophic factor (MANF) and conserved dopamine neurotrophic factor (CDNF) protect midbrain dopaminergic neurons that degenerate in Parkinson's disease. Each GDNF ligand binds a specific coreceptor GDNF family receptor (GFR ), leading to the formation of a heterotetramer complex, which then interacts with receptor tyrosine kinase RET, the signalling receptor. The present work describes the structural and biochemical characterization of the GDNF-GFR 1 complex and the MANF and CDNF proteins. 92 pp. Englisch. Bookseller Inventory # 9783838322469

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Book Description LAP Lambert Acad. Publ. Nov 2009, 2009. Taschenbuch. Book Condition: Neu. This item is printed on demand - Print on Demand Neuware - Four GDNF ligands (GDNF, neurturin, artemin and persephin), and mesencephalic astrocyte-derived neurotrophic factor (MANF) and conserved dopamine neurotrophic factor (CDNF) protect midbrain dopaminergic neurons that degenerate in Parkinson's disease. Each GDNF ligand binds a specific coreceptor GDNF family receptor (GFR ), leading to the formation of a heterotetramer complex, which then interacts with receptor tyrosine kinase RET, the signalling receptor. The present work describes the structural and biochemical characterization of the GDNF-GFR 1 complex and the MANF and CDNF proteins. 92 pp. Englisch. Bookseller Inventory # 9783838322469

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Book Description Book Condition: New. Publisher/Verlag: LAP Lambert Academic Publishing | The structural and functional studies of GDNF and MANF/CDNF family of neurotrophic factors | Four GDNF ligands (GDNF, neurturin, artemin and persephin), and mesencephalic astrocyte-derived neurotrophic factor (MANF) and conserved dopamine neurotrophic factor (CDNF) protect midbrain dopaminergic neurons that degenerate in Parkinson's disease. Each GDNF ligand binds a specific coreceptor GDNF family receptor (GFR ), leading to the formation of a heterotetramer complex, which then interacts with receptor tyrosine kinase RET, the signalling receptor. The present work describes the structural and biochemical characterization of the GDNF-GFR 1 complex and the MANF and CDNF proteins. | Format: Paperback | Language/Sprache: english | 140 gr | 92 pp. Bookseller Inventory # K9783838322469

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Book Description LAP Lambert Acad. Publ., 2010. Paperback. Book Condition: New. Language: English . Brand New Book. Four GDNF ligands (GDNF, neurturin, artemin and persephin), and mesencephalic astrocyte-derived neurotrophic factor (MANF) and conserved dopamine neurotrophic factor (CDNF) protect midbrain dopaminergic neurons that degenerate in Parkinson s disease. Each GDNF ligand binds a specific coreceptor GDNF family receptor ? (GFR?), leading to the formation of a heterotetramer complex, which then interacts with receptor tyrosine kinase RET, the signalling receptor. The present work describes the structural and biochemical characterization of the GDNF-GFR?1 complex and the MANF and CDNF proteins. Bookseller Inventory # KNV9783838322469

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