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New Horizons in Predictive Toxicology (Hardcover)

Royal Society of Chemistry

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ISBN 10: 1849730512 / ISBN 13: 9781849730518
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Hardcover. Modelling and simulation technologies have improved dramatically over the past decade and their applications in toxicity prediction and risk assessment are of great importance. Such approa.Shipping may be from multiple locations in the US or from the UK, depending on stock availability. 732 pages. 1.184. Bookseller Inventory # 9781849730518

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Title: New Horizons in Predictive Toxicology (...

Binding: Hardcover

Book Condition:New

About this title

Synopsis:

Modelling and simulation technologies have improved dramatically over the past decade and their applications in toxicity prediction and risk assessment are of great importance. Such approaches will become increasingly necessary as industrial chemicals advance and as new pharmaceuticals enter the market. In this comprehensive discussion of predictive toxicology and its applications, leading experts express their views on the technologies currently available and the potential for future developments. The book covers a wide range of topics including the in silico, in vitro and in vivo approaches being used in the safety assessment of chemical substances. It reflects the growing and urgent need to strengthen our ability to predict the risks posed by industrial and pharmaceutical chemicals in humans. Extensive information on the use of current animal models used for various toxicities and target-mediated toxicities is included. Also discussed are the recently introduced regulatory initiatives.

Book Description:

Toxicology continues to be a major cause of product attrition; in addition the implementation of REACH is having an impact on our need to continually improve our capabilities to predict potential safety concerns earlier. This unique book provides a comprehensive review and discussion on the status of predictive toxicology and its application. This is a critical hot topic and an area of continuing importance and the book is timely in providing a leading and expert treatise. Chapters cover the current approaches in predictive toxicology including in silico, in vitro and in vivo. In addition, examples of how these approaches can be integrated to improve the safety assessment to humans are covered. There is also discussion of current approaches for biomarker identification and application (eg omics approaches).

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