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Peptide Nucleic Acids and Markers

Prasanna Ramani

ISBN 10: 384432805X / ISBN 13: 9783844328059
Published by LAP Lambert Academic Publishing
New Condition: New Soft cover
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About this Item

232 pages. Dimensions: 8.6in. x 5.8in. x 0.6in.The remarkable binding properties of Peptide Nucleic Acids (PNA), the so called artificial DNAs, have spawned a rapidly expanding new field of research, where the targets are the synthesis of PNAs and PNA analogues, and their applications as therapeutics, DNA diagnostics, tools in biotechnology and much more. PNA is linked to various scientific disciplines, few includes medicinal chemistry, biochemistry, molecular biology, immunology and drug development. This book describes the design, synthesis and analytical studies of labeled nucleic acid analog. Basic methods for the synthesis of PNA monomeroligomer are incorporated. Further, the syntheses of electrochemical and fluorescently labeled PNA monomersoligomers are dealt-with in detail. The final part of the book discusses about the possibility of using linkersspacers to carry marker to link PNA monomeroligomer. This book would be an inspiration for undergraduatespostgraduates and experienced researchers as it provides an easy introduction to the optimal use of PNA in various disciplines. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Bookseller Inventory # 9783844328059

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Bibliographic Details

Title: Peptide Nucleic Acids and Markers

Publisher: LAP Lambert Academic Publishing

Binding: Paperback

Book Condition:New

Book Type: Paperback

About this title

Synopsis:

The remarkable binding properties of ‘Peptide Nucleic Acids’ (PNA), the so called artificial DNAs, have spawned a rapidly expanding new field of research, where the targets are the synthesis of PNAs and PNA analogues, and their applications as therapeutics, DNA diagnostics, tools in biotechnology and much more. PNA is linked to various scientific disciplines, few includes medicinal chemistry,biochemistry, molecular biology, immunology and drug development. This book describes the design, synthesis and analytical studies of labeled nucleic acid analog. Basic methods for the synthesis of PNA monomer/oligomer are incorporated. Further, the syntheses of electrochemical and fluorescently labeled PNA monomers/oligomers are dealt-with in detail. The final part of the book discusses about the possibility of using linkers/spacers to carry marker to link PNA monomer/oligomer. This book would be an inspiration for undergraduates/postgraduates and experienced researchers as it provides an easy introduction to the optimal use of PNA in various disciplines.

About the Author:

Prasanna Ramani is an Assistant Professor at Amrita University, Coimbatore(India).He received UNESCO grant in collaboration with ICTP during his postdoctoral work at Center for biomolecular Interdisciplinary Studies & Industrial research(CISI), Milan(IT)and he got his Ph.D from University of Milan.His focus is on peptide & medicinal chemistry.

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