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Pharmaceutical and Biomedical Applications of Capillary Electrophoresis (Progress in Pharmaceutical and Biomedical Analysis Volume 2)New TYor

Lunte, Susan M. And Donna M. Radzik

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ISBN 10: 0080420141 / ISBN 13: 9780080420141
Published by Pergamon Press, New York, 1996
Used Condition: Very Good Ex-Library Cond Book Hardcover
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Blue glossy boards. 511 pgs. Usual library markings. Clean and tightly bound. CHAPTER TITLES: principles of capillary electrophoresis; column technologies for electrophoresis; electrokinetic chromatography; optical detection strategies in capillary electrophoresis; capillary electrophresis/mass spectrometry; electrochemical detection for capillary electrophoresis; sample preparation for capillary electrophoresis; capillary electrophoresis in the study of amino acids; capillary electrophoresis of proteins and peptides; separation of nucleic acids and oligonucleotides and sequencing of DNA fragments by capillary electrophoresis; the use of capillary electrophresis in pharmaceutical development; and capillary electrophresis-based methods for in vivo analysis: single cell analysis and microdialysis sampling. Size: 8vo - over 7¾" - 9¾" tall. Bookseller Inventory # B034314

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Bibliographic Details

Title: Pharmaceutical and Biomedical Applications ...

Publisher: Pergamon Press, New York

Publication Date: 1996

Binding: Hardcover

Book Condition: Very Good Ex-Library Cond Book

Book Type: Book

About this title


The book describes the theory and applications of Capillary Electrophoresis (CE) in the field of pharmaceutical and biomedical analysis. It is targeted towards users who are intimately involved in analytical problems, especially those which involve small samples. This book presents the technique of capillary electrophoresis from the point of view of the serious hands-on use in the field of pharmaceutical and biomedical analysis. An overview of general theory is presented to acquaint the novice with the fundamental principles. A more theoretical approach is taken in the presentation of electrokinetic chromatography. The next chapter discusses advances in column technologies, the preceding chapters having provided a foundation as to how separations occur. In the next three chapters, recognized experts in their fields present fundamentals and state-of-the-art techniques in the areas of optical, electrochemical and mass spectrometric detection. The major focus of the remaining chapters is on applications. This includes the analysis of pharmaceuticals, amino acids and peptides, macromolecules, nucleosides, nucleotides and oligonucleotides. The use of CE for analysis of small ions and separation of biological particles is also discussed. The issue of sample preparation for analysis by CE is addressed, especially as it relates to clinical analysis.

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