The Pharmacology of Monoclonal Antibodies (Handbook of Experimental Pharmacology)

Gordon P. Moore

Published by Springer Verlag
ISBN 10: 038757123X / ISBN 13: 9780387571232
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Synopsis: A sample of the most exciting developments in the cloning, manipulation, expression and application of genetically-engineered monoclonal antibodies. This rapidly-evolving field has witnessed the PCR combinatorial cloning of vast immunological diversity, in vitro mutagenesis of MAbs, MAbs created by transgenic animals, novel expression systems in plants, animals and lower systems, as well as a rich variety of genetically modified MAbs as potential therapeutic agents. Leading scientists from academia and industry present their own findings as well as short reviews of these research areas.

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Title: The Pharmacology of Monoclonal Antibodies (...
Publisher: Springer Verlag
Binding: Hardcover
Book Condition: VERY GOOD

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Rosenberg, Martin; Moore, Gordon P.; Balint, Robert Frederick
Published by Springer Verlag, Secaucus, New Jersey, U.S.A. (1994)
ISBN 10: 038757123X ISBN 13: 9780387571232
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Book Description Springer Verlag, Secaucus, New Jersey, U.S.A., 1994. Hardcover. Condition: Very Good Ex-Library Cond Book. 406 pgs. Chapters cover: human monoclonal antibody technology; recombinant therapeutic human monoclonal antibodies; transgenic approaches to human monoclonal antibodies; genetically engineered monoclonal antibodies; applications for E coli-derived humanized Fab fragments: efficient construction of bispecific antibodies; MAb conjugates and fusions; imunotoxins; antibody-enzyme proteins and bispecific antibodies; three generations of recombinant CD4 molecules; combinatorial libraries: chemical and biological approaches to catalytic antibodies; the combinatorial approach to human antibodies; expression of MAbs/MAb fragments: antibodies from E coli, structure, function and uses of antibodies from transgenic plants and animals, some aspects of monoclonal antibody production; medical applications: prospects for cancer imaging and therapy with radioimmunoconjugates, clinical experimence with murine, human and genetically engineered monoclonal antibodies, anti-idiotypic monoclonal antibodies: novel approach to immunotherapy; subject index. Navy blue boards with orange/white lettering. Usual library markings. Clean and tightly bound. Size: 8vo - over 7" - 9" tall. Book. Seller Inventory # B034826

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Gordon P. Moore
Published by Springer Verlag (1994)
ISBN 10: 038757123X ISBN 13: 9780387571232
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Book Description Springer Verlag, 1994. Condition: UsedAcceptable. book. Seller Inventory # M038757123X_4

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Gordon P. Moore
Published by Springer Verlag (1994)
ISBN 10: 038757123X ISBN 13: 9780387571232
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Book Description Springer Verlag, 1994. Condition: New. book. Seller Inventory # M038757123X

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