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Prions Prions Prions (Current Topics in Microbiology and Immunology)

ISBN 10: 3642646409 / ISBN 13: 9783642646409
Published by Springer, 2011
Used Condition: Good
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3642646409 May have signs of use, may be ex library copy. Book Only. Used items do not include access codes, cd's or other accessories, regardless of what is stated in item title. Bookseller Inventory # Z3642646409Z3

Bibliographic Details

Title: Prions Prions Prions (Current Topics in ...

Publisher: Springer

Publication Date: 2011

Book Condition:Good

About this title

Synopsis:

A series of remarkable discoveries in the past three decades have led to the molecular and genetic characterization of the transmissible pathogen causing scrapie in animals and a quartet of human illnesses: kuru, Jakob-Creutzfeld disease, Gerstmann-Sträussler-Scheinker disease, and fatal familial insomnia. To distinguish this pathogen from viruses and viroids, the term "prion" was introduced to emphasize its proteinaceous and infectious nature.
Stanley B. Prusiner, editor of this volume, was awarded the 1997 Nobel Prize in Physiology and Medicine for his pioneering discovery of prions. The book reviews advances in studies of prions, which - as considereable evidence indicates - are novel pathogens composed only of protein.

From the Back Cover:

A series of remarkable discoveries in the past three decades have led to the molecular and genetic characterization of the transmissible pathogen causing scrapie in animals and a quartet of human illnesses: kuru, Jakob-Creutzfeld disease, Gerstmann-Straussler-Scheinker disease, and fatal familial insomnia. To distinguish this pathogen from viruses and viroids, the term "Prion" was introduced to emphasize its proteinacous and infectious nature. This book reviews recent advances in studies of prions. Considerable evidence now indicates that prions are novel pathogens composed only of protein. The conversion of a normal cellular protein into a pathologic isoform is the fundamental event in prion replication and the pathogenesis of prion diseases.

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