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Synopsis: This well-organized and clearly written text has a unique focus on methods of identifying the joint effects of genes and environment on disease patterns. It follows the natural sequence of research, taking readers through the study designs and statistical analysis techniques for determining whether a trait runs in families, testing hypotheses about whether a familial tendency is due to genetic or environmental factors or both, estimating the parameters of a genetic model, localizing and ultimately isolating the responsible genes, and finally characterizing their effects in the population. Examples from the literature on the genetic epidemiology of breast and colorectal cancer, among other diseases, illustrate this process. Although the book is oriented primarily towards graduate students in epidemiology, biostatistics and human genetics, it will also serve as a comprehensive reference work for researchers. Introductory chapters on molecular biology, Mendelian genetics, epidemiology, statistics, and population genetics will help make the book accessible to those coming from one of these fields without a background in the others. It strikes a good balance between epidemiologic study designs and statistical methods of data analysis.
About the Author: Duncan C Thomas, Ph.D., is Professor of Preventive Medicine, Director of the Biostatistics Division, and Verna R Richter Chair in Cancer Research at the University of Southern California Keck School of Medicine. His primary research interest has been in the development of statistical methods for cancer epidemiology, but he also has wide-ranging interest in both environmental and genetic epidemiology. Dr Thomas also chairs organizing committees for the Genetic Analysis Workshop and the Informatics Consortium for the NCI Cooperative Family Registries for Breast and Colorectal Cancer, and he is a past President of the International Genetic Epidemiology Society.
Title: Statistical Methods in Genetic Epidemiology
Publisher: Oxford University Press, USA
Publication Date: 2004
Book Condition: Good
Edition: 1st Edition.
Book Description Oxford University Press. Book Condition: Very Good. Goodwill helps change lives through the power of work. Bookseller Inventory # 6-B-5-0913
Book Description Oxford University Press. Book Condition: Good. A copy that has been read, but remains in clean condition. All pages are intact, and the cover is intact (including dust cover, if applicable). The spine and cover may show signs of wear. Pages can include limited notes and highlighting, and the copy can This item was a donation to Goodwill of Greater Washington. Thanks for your order from Goodwill of Greater Washington. Bookseller Inventory # F-07-03080
Book Description Oxford University Press, 2004. Hardcover. Book Condition: Near Fine. Dust Jacket Condition: Near Fine. 1st Edition. Clean and unmarked. Like new. Bookseller Inventory # 037585
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Book Description Oxford University Press, 2004. Hardcover. Book Condition: Fine. With the exception of owner's address label on front free endpaper and embossment stamp on title page, the book appears to be unread. Ships within 24 hours, carefully wrapped. BNCTucsonbooks ships daily. Proceeds from the sales of books support an endowed scholarship to Brandeis University, Waltham Mass. Bookseller Inventory # mon0000058682
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Book Description Oxford University Press, USA, 2004. Hardcover. Book Condition: Used: Acceptable. Bookseller Inventory # SONG019515939X
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Book Description Oxford University Press, 2017. Hardcover. Book Condition: Very Good. Great condition with minimal wear, aging, or shelf wear. This item is printed on demand. Bookseller Inventory # P02019515939X
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