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Stem Cells and Extracellular Matrices

Lakshmi Kiran Chelluri

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ISBN 10: 1615043764 / ISBN 13: 9781615043767
Published by Morgan & Claypool
New Condition: New Soft cover
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82 pages. Dimensions: 8.4in. x 5.8in. x 0.7in.Stem cells have great potential in regenerative medicine and tissue injury. Regulation of stem cell homeostasis in a 3D microenvironment is controlled by the niche components that influence stem cell fate, regulation, and function. It is therefore necessary to understand the mechanisms of cellcell interaction, molecular cross talk between stem cells and their extracellular matrix (ECM) environment. The adhesion molecules play a pivotal role in establishing the cellcell contact and subsequent integration with the ECM. This understanding is the basis for establishing design criteria for biomimetic. The integrated approach by biologists, material science engineers, biomedical engineers, and clinicians is the key in the development of tissue engineered constructs for effective translation to clinics. Table of Contents: Abbreviations Introduction to Stem Cell Biology and Niche Components ECMStructure and Organization ECM Control, Regulation on Stem Cell Fate and Function ECM and Stem Cell Cultures Acknowledgments Bibliography Author Biography Titles of Related Interest This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Bookseller Inventory # 9781615043767

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Title: Stem Cells and Extracellular Matrices

Publisher: Morgan & Claypool

Binding: Paperback

Book Condition:New

Book Type: Paperback

About this title

Synopsis:

Stem cells have great potential in regenerative medicine and tissue injury. Regulation of stem cell homeostasis in a 3D microenvironment is controlled by the niche components that influence stem cell fate, regulation, and function. It is therefore necessary to understand the mechanisms of cell–cell interaction, molecular cross talk between stem cells and their extracellular matrix (ECM) environment. The adhesion molecules play a pivotal role in establishing the cell–cell contact and subsequent integration with the ECM. This understanding is the basis for establishing design criteria for biomimetic. The integrated approach by biologists, material science engineers, biomedical engineers, and clinicians is the key in the development of tissue engineered constructs for effective translation to clinics.

Table of Contents: Abbreviations / Introduction to Stem Cell Biology and Niche Components / ECM—Structure and Organization / ECM Control, Regulation on Stem Cell Fate and Function / ECM and Stem Cell Cultures / Acknowledgments / Bibliography / Author Biography / Titles of Related Interest

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