The Ubiquitin-Proteasome Proteolytic System: From Classical Biochemistry to Human Diseases

Published by WORLD SCIENTIFIC PUBLISHING, 2003
ISBN 10: 9812381007 / ISBN 13: 9789812381002
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Item may show signs of shelf wear. Pages may include limited notes and highlighting. Includes supplemental or companion materials if applicable. Access codes may or may not work. Connecting readers since 1972. Customer service is our top priority. Bookseller Inventory #

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Synopsis: Ubiquitin-proteasome-dependent proteolysis is central to an incredible multitude of processes in all eukaryotes, including the cell cycle, cell growth and differentiation, embryogenesis, apoptosis, signal transduction, DNA repair, regulation of transcription and DNA replication, transmembrane transport, endocytosis, stress responses, antigen presentation and other aspects of the immune response, the functions of the nervous system including circadian rhythms, axon guidance and acquisition of memory.This book tells the story of the ubiquitin system as we currently know it: from the regulation of basic cellular processes to quality control and the pathogenetic mechanisms of disease, from X-ray crystallography of the 26S proteasome to the interaction between substrates and their ligases, to the development of mechanism-based drugs, and to target-specific aberrant processes.

Review: Will be of great interest to people interested in the regulation of cell processes. -- Cell Biochemistry and Function

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Title: The Ubiquitin-Proteasome Proteolytic System:...
Publisher: WORLD SCIENTIFIC PUBLISHING
Publication Date: 2003
Binding: Hardcover
Book Condition: Good

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