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Radhey Mohan Singh

ISBN 10: 3639187989 / ISBN 13: 9783639187984
Published by VDM Verlag, 2009
Condition: Good Soft cover
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Bibliographic Details


Publisher: VDM Verlag

Publication Date: 2009

Binding: Paperback

Book Condition: Good

About this title


Vilsmeier-Haack reaction has been recognised as one of the most relevant tool both of industrial and academic importance. The reagent undergoes different courses of reactions, namely formylation, acylhaloaddition, cyclization, ring annulation and dehydroxylation. The work entitled, ?Vilsmeier-Haack Reagent Aided Synthesis and Quinoline based Fused Heterocyclic Compounds?, deals the brief survey on the applications of Vilsmeier-Haack reagent on the organic compounds containing different functional groups and discussed the synthesis of 2-chloro-3- formylquinolines and 2-chloro-3-formylbenzo[f] quinolines, respectively from the reaction of acetanilides and N-acetyl-2-naphthylamine using Vilsmeier-Haack reagent.Further, the various chemical evidences are described to establish the structure of the compounds such as the conversion of the 3-formyl group into the anils, oximes, hydrazones, semicarbazones, nitriles, esters, acetals, homoallyl and homopropargyl alcohols and substitution at the 2-chloro group by sulphur, oxygen and nitrogen nucleophiles.

About the Author:

Prof. R. M. Singh received Ph.D. from Banaras Hindu University, Varanasi, India under the supervision of Prof. S.M. Verma and joined as a lecturer in the same department. He received postdoctoral training with Prof. A. Rieker, Tubingen University,Germany. He has been author of a number of papers in national and international journals.

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